98995-93-8

Basic information

• Product Name: Benzeneacetaldehyde, a-methoxy-, oxime
• CAS NO: 98995-93-8
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Mol File: 98995-93-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetaldehyde, a-methoxy-, oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetaldehyde, a-methoxy-, oxime(98995-93-8)
• EPA Substance Registry System: Benzeneacetaldehyde, a-methoxy-, oxime(98995-93-8)

Safety Data

• Hazardous Substances Data: 98995-93-8(Hazardous Substances Data)

Upstream product

• 20698-91-3 (R)-methyl mandelate 
• 611-71-2 (R)-Mandelic Acid 
• 32174-46-2 methyl (R)-(-)-2-methoxy-2-phenylacetate 
• 72538-27-3 (-)-(R)-2-methoxy-2-phenylacetaldehyde 
• 19190-53-5 2-methoxy-2-phenylacetaldehyde 
• 67-56-1 methanol 
• 3425-99-8 (1,2-dibromo-2-nitroethyl)benzene 
• 102-96-5 (2-nitroethenyl)benzene 

Downstream Products

• 101639-88-7 (S)-6-Benzyl-4-hydroxy-4-((R)-methoxy-phenyl-methyl)-[1,3]oxazinan-2-one 
• 101639-86-5 1,5-diphenyl-4-hydroxy-1-methoxy-2-pentanone 
• 101639-84-3 5-benzyl-4,5-dihydro-3-(α-methoxy-benzyl)-isoxazole 
• 19190-53-5 2-methoxy-2-phenylacetaldehyde 
• 13031-13-5 2-methoxy-2-phenylacetonitrile 

Relevant articles and documents

Synthesis of Nitriles from Aldoximes and Primary Amides Using XtalFluor-E

The dehydration reaction of aldoximes and amides for the synthesis of nitriles using [Et2NSF2]BF4 (XtalFluor-E) is described. Overall, the reaction proceeds rapidly (normally 1 h) at room temperature in an environmentally benign solvent (EtOAc) with only a slight excess of the dehydrating agent (1.1 equiv). A broad scope of nitriles can be prepared, including chiral nonracemic ones. In addition, in a number of cases, further purification of the nitrile after the workup was not required.

Highly efficient and catalytic conversion of aldoximes to nitriles

(Matrix Presented) Catalytic dehydration of aldoximes can be performed highly efficiently with a catalyst system of [RuCl2(p-cymene)]2/molecular sieves under essentially neutral and mild conditions, and various types of cyano compounds are produced in good to excellent yields.