342634-33-7

Upstream product

• 60-29-7 diethyl ether 
• 70127-96-7 2-amino-3-methoxy-benzaldehyde 
• 93-55-0 1-phenyl-propan-1-one 
• 112955-06-3 8-methoxy-3-methylquinoline 

Downstream Products

• 342634-34-8 2-phenyl-3-methyl-8-hydroxyquinoline 

Relevant academic research and scientific papers

2-Phenyl-quinoline derivatives, preparation method and therapeutic use thereof

Compounds of general formula (I) 1in which: A represents a hydrogen atom or a hydroxyl, B represents a hydrogen atom or a C1-3 alkyl group, R1 represents a phenyl optionally substituted with a halogen, a hydroxyl, a C1-3 alkoxy, C1-3 alkyl, C1-3 fluoroalkyl or C1-2 perfluoroalkyl group, R2, R3 and R6, which may be identical or different, each represent a hydrogen atom, a halogen, a C1-6 alkyl or C2-6 alkenyl group, R4 and R5, which may be identical or different, each represent a hydrogen atom, a C1-6 alkyl, C2-6 alkenyl or C3-6 cycloalkyl group, or R4 and R5 together form a C2-6 alkylene or C3-6 alkenylene chain to give, with the nitrogen to which they are attached, a heterocycle, this heterocycle optionally being substituted with a C1-4 alkyl group. Therapeutic use.

2-arylquinoline derivatives, preparation and therapeutic use thereof

Compounds of general formula (I) in which: A represents a hydrogen atom, a hydroxyl, a C1-3alkoxy group, a hydroxy(C1-6alkyl) group, a (C1-3alkoxy)(C1-3alkyl) group, a thiol, (C1-6alkyl)sulfanyl or a halogen; B and D represent, independently of one another, a hydrogen atom, a C1-6alkyl group, a fluoro(C1-6alkyl) group or a perfluoro(C1-2alkyl) group or B and D together from an oxo; R1represents a phenyl, a naphthyl or a heteroaryl comprising 4 or 5 carbon atoms; R2and R3represent, independently of one another, a hydrogen atom, a halogen or a C1-6alkyl group, R4represents a hydrogen atom, a hydroxyl or a halogen, and R5and R6represent, independently of one another, a hydrogen atom, a C1-6alkyl group, a C2-6alkenyl group, a C3-6cycloalkyl group, a C3-6cycloalkenyl group, a fluoro(C1-6alkyl) group or a perfluoro(C1-2alkyl) group or R5and R6together form a C2-6alkylene chain or a C3-6alkenylene chain, to give, with the nitrogen to which they are attached, a heterocycle, this heterocycle optionally being substituted by a C1-4alkyl group; and their salts.