34272-40-7

Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-Ethylpiperidine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to enhance the reactivity and functionality of the compounds being developed. It contributes to the creation of new drugs with improved therapeutic properties.
Used in Agrochemical Production:
(S)-2-Ethylpiperidine is used as a building block in the production of agrochemicals, where it plays a role in the development of pesticides and other agricultural chemicals that help protect crops and enhance yield.
Used in Dye and Perfume Industries:
(S)-2-Ethylpiperidine is used as a raw material in the formulation of dyes and perfumes, contributing to the creation of vibrant colors and distinct scents in various consumer products.
Used in Organic Compound Synthesis:
(S)-2-Ethylpiperidine is used as a versatile reagent in the synthesis of organic compounds, facilitating the development of new chemical entities with potential applications in various industries.

Upstream product

• 1484-80-6 2-ethylpiperidine 
• 1643770-97-1 (S)-2,2-dimethyl-5-oxo-3-(2-phenylacetyl)imidazolidin-1-yl 2-methoxy-2-phenylacetate 

Downstream Products

• 247934-45-8 2(S)-ethyl 1-[(1-phenyl 3-isoquinolyl) carbonyl]piperidine 
• 558479-15-5 (2S)-ethyl-1-[(R)-oxiranylmethyl] piperidine 

Relevant academic research and scientific papers

Stereoelectronic basis for the kinetic resolution of n-heterocycles with chiral acylating reagents

The kinetic resolution of N-heterocycles with chiral acylating agents reveals a previously unrecognized stereoelectronic effect in amine acylation. Combined with a new achiral hydroxamate, this effect makes possible the resolution of various N-heterocycles by using easily prepared reagents. A transition-state model to rationalize the stereochemical outcome of this kinetic resolution is also proposed.

Expanded substrate scope and catalyst optimization for the catalytic kinetic resolution of N-heterocycles

The scope, reactivity, and selectivity of the chiral hydroxamic acid-catalyzed kinetic resolution of chiral amines are improved by a new catalyst structure and a more environmentally friendly reaction protocol. In addition to increasing selectivity across all substrates, these conditions make possible the resolution of N-heterocycles containing lactams or other basic functional groups that can inhibit the catalyst.

THERAPEUTIC COMBINATIONS COMPRISING A SELECTIVE ESTROGEN RECEPTOR MODULATOR AND A SELECTIVE ANDROGEN RECEPTOR MODULATOR

This invention relates to a pharmaceutical combination of a selective estrogen receptor modulator (SERM) and a selective androgen receptor modulator (SARM). Particularly, this invention relates to a pharmaceutical composition comprising cis-6-phenyl-5-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)-5,6,7,8-tetrahydronapthalene-2-ol, or a pharmaceutically acceptable salt thereof; and a selective androgen receptor modulator. This invention also relates to methods of treatment using the pharmaceutical composition comprising cis-6-phenyl-5-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)-5,6,7,8-tetrahydronapthalene-2-ol, or a pharmaceutically acceptable salt thereof; and a selective androgen receptor modulator. Particularly, this invention is directed to methods to prevent and/or restore age-related decline in muscle mass and strength, treat a wasting disease, treat a condition that prevents with low bone mass, increase muscle mass, increase lean body mass, decrease fat body mass, treat bone fracture and muscle damage and treat female sexual dysfunction in mammals, including humans.

BENZONITRILE DERIVATIVES TO TREAT MUSCULOSKELETAL FRAILTY

This invention relates to novel amino substituted benzonitrile derivatives and to pharmaceutical compositions containing the novel amino substituted benzonitrile derivatives. This invention also relates to methods of treatment using amino substituted benzonitrile derivatives to prevent and/or restore age-related decline in muscle mass and strength, treat a wasting disease, treat a condition that prevents with low bone mass, increase muscle mass, increase lean body mass, decrease fat body mass, and treat bone fracture and muscle damage in mammals, including humans.