558479-15-5Relevant articles and documents
1,3-Diaminopropan-2-ol Sulfonamides as potent and selective inhibitors of the glycine transporter type 1
Rahman, Shahzad S.,Coulton, Steven,Herdon, Hugh J.,Joiner, Graham F.,Jin, Jian,Porter, Roderick A.
, p. 1741 - 1745 (2007)
High throughput screening led to the discovery of a novel series of 1,3-diaminopropan-2-ol sulfonamides as selective GlyT-1 inhibitors. Structure-activity relationships of this novel series and optimisation of the initial hit that led to the identificatio