342808-49-5Relevant articles and documents
PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS
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Paragraph 0370, (2019/10/23)
The present disclosure provides, inter alia, Compounds of Formulae IA, IB, IC, IIA, IIB and IIC or pharmaceutically acceptable salts thereof that are modulators of the C5a receptor. Also provided are pharmaceutical compositions and methods of use including the treatment of diseases or disorders involving pathologic activation from C5a and non-pharmaceutical applications.
Novel 1,4-benzodiazepine derivatives with antiproliferative properties on tumor cell lines
Dourlat, Jennifer,Liu, Wang-Qing,Gresh, Nohad,Garbay, Christiane
, p. 2527 - 2530 (2008/02/01)
Novel 1,4-benzodiazepine compounds were synthesized and evaluated for their ability to inhibit the proliferation of tumor cells. Some compounds revealed activities in the micromolar range and were more efficient than reference compound Ro 5-4864. Prelimin