34284-42-9Relevant academic research and scientific papers
Conversion of Epoxides to 1,3-Dioxolanes Catalyzed by Tin(II) Chloride
Vyvyan, James R.,Meyer, Jennifer A.,Meyer, Korin D.
, p. 9144 - 9147 (2003)
Anhydrous tin(II) chloride is an efficient catalyst for the reaction of epoxides with acetone to prepare 2,2-dimethyl-1,3-dioxolanes (acetonides) in good to excellent yields. Mono-, di-, and trisubstituted epoxides participate equally well in this diastereospecific reaction. The use of single enantiomer epoxides under the reported conditions results in significant erosion of optical activity.
