34288-06-7

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
(2-BENZYLOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE is used as a reagent in the synthesis of heterocyclic compounds and bioactive molecules, which are crucial for the development of new pharmaceuticals. Its unique structure allows for the creation of a variety of chemical entities with potential therapeutic applications.
Used in Organic Chemical Synthesis:
In the field of organic chemistry, (2-BENZYLOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE serves as a versatile reagent, facilitating the formation of complex organic molecules through various synthetic pathways.
Used in Specialty Chemicals Production:
(2-BENZYLOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE is utilized in the production of specialty chemicals such as dyes, pigments, and polymers, where its specific chemical properties contribute to the desired characteristics of these materials.
Used in Research Laboratories:
In academic and industrial research settings, (2-BENZYLOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE is employed for conducting experiments and exploring new chemical reactions, potentially leading to the discovery of novel compounds and applications.

Upstream product

• 20012-63-9 o-(benzyloxy)aniline 

Downstream Products

• 937177-65-6 2-(7-benzyloxy-2-phenyl-1H-indol-3-yl)-N-[3-(4-hydroxy-phenyl)-1-methyl-propyl]-acetamide 
• 1245795-18-9 N-(benzyloxycarbonyl)-L-glutamic acid 1-(benzyl ester) 5-[(2-benzyloxy-phenyl)-hydrazide] 
• 937177-87-2 N-[3-(4-methoxymethoxy-phenyl)-1-methyl-propyl]-2-[2-phenyl-7-(5-piperidin-1-yl-pentyloxy)-1H-indol-3-yl]-acetamide 
• 937177-86-1 N-[3-(4-methoxymethoxy-phenyl)-1-methyl-propyl]-2-[2-phenyl-7-(4-piperidin-1-yl-butoxy)-1H-indol-3-yl]-acetamide 
• 937177-85-0 N-[3-(4-methoxymethoxy-phenyl)-1-methyl-propyl]-2-[2-phenyl-7-(3-piperidin-1-yl-propoxy)-1H-indol-3-yl]-acetamide 
• 937177-84-9 N-[3-(4-methoxymethoxy-phenyl)-1-methyl-propyl]-2-[2-phenyl-7-(2-piperidin-1-yl-ethoxy)-1H-indol-3-yl]-acetamide 
• 937177-69-0 2-(7-benzyloxy-2-phenyl-1H-indol-3-yl)-N-[3-(4-methoxymethoxy-phenyl)-1-methyl-propyl]-acetamide 
• 937177-73-6 2-(7-hydroxy-2-phenyl-1H-indol-3-yl)-N-[3-(4-methoxymethoxy-phenyl)-1-methyl-propyl]-acetamide 

Relevant academic research and scientific papers

Design, synthesis and biological evaluation of glutamic acid derivatives as anti-oxidant and anti-inflammatory agents

A series of glutamic acid derivatives was synthesized and evaluated for their antioxidant activity and stability. We found several potent and stable glutamic acid derivatives. Among them, compound 12b exhibited good in vitro activity, chemical stability and cytotoxicity. A prototype compound 12b showed an anti-inflammatory effect in LPS-stimulated RAW 264.7 cell lines and in a zebrafish model.

METHOD FOR SYNTHESIZING RAMALIN AND RAMALIN PRECURSOR BY USING GLUTAMIC ACID DERIVATIVE AND HYDROXY ANILINE OR HYDROXY ANILINE HAVING PROTECTED HYDROXY GROUP

Disclosed is a method of the synthesis of ramalin. It comprises reacting a glutamic acid derivative, which is prepared using alkylchloroformate, with a hydrazine salt compound, which is prepared from hydroxy aniline, whether protected or not. The synthesis method allows ramalin, excellent in antioxidant and anti-inflammatory activity, to be simply synthesized at stable yield even without use of a highly toxic solvent such as DMF. In addition, the method is cost competitive, and provides ramalin at high efficiency, thus enabling the mass production of ramalin.

A novel aryl-hydrazide from the marine lichen Lichina pygmaea: Isolation, synthesis of derivatives, and cytotoxicity assays

A new aryl-hydrazide l-glutamic acid derivative, pygmeine (3), was isolated from a methanolic extract of Lichina pygmaea, a marine lichen. Synthetic derivatives obtained via a two-step coupling of l-glutamic acid with phenylhydrazine moieties were useful