342885-53-4 Usage
General Description
2,2,2-trifluoro-1-(1-methanesulfonyl-1H-indol-3-yl)-ethanone, also known as ICI-199441, is a synthetic fluoroalkenyl ketone compound with potential anti-inflammatory and analgesic properties. It inhibits the production of pro-inflammatory cytokines and enzymes, and reduces the migration of leukocytes to the site of inflammation. This chemical is a potent inhibitor of the enzyme cyclooxygenase-2 (COX-2), which plays a key role in the production of prostaglandins, important mediators of inflammation and pain. ICI-199441 has been studied for its potential use in the treatment of inflammatory and pain-related conditions, and has shown promising results in preclinical trials.
Check Digit Verification of cas no
The CAS Registry Mumber 342885-53-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,2,8,8 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 342885-53:
(8*3)+(7*4)+(6*2)+(5*8)+(4*8)+(3*5)+(2*5)+(1*3)=164
164 % 10 = 4
So 342885-53-4 is a valid CAS Registry Number.
342885-53-4Relevant academic research and scientific papers
Kurkin,Karchava,Yurovskaya
, p. 1141 - 1148 (2000)
The reaction of 1-(methylsulfonyl)- and 1-(phenylsulfonyl)indoles with N,N-dibenzylamino alcohols leads to the formation of a mixture of isomeric 1-(β-aminoethyl)indoles.
