342898-59-3

Upstream product

• 342898-57-1 (R)-N-(tert-butoxycarbonyl)-2-(5-benzyloxy-2-bromophenoxy)-1-(4-benzyloxyphenyl)ethylamine 
• 199393-31-2 (R)-2-(tert-butoxycarbonyl)amino-2-(4-benzyloxyphenyl)ethanol 
• 70120-19-3 5-(benzyloxy)-2-bromophenol 
• 342898-58-2 (R)-2-(5-benzyloxy-2-bromophenoxy)-1-(4-benzyloxyphenyl)ethylamine 
• 76144-87-1 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl 

Relevant academic research and scientific papers

NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS

The present invention provides novel heterocyclic compounds of Formula I wherein A, B, E, ring Z, Y, L, ring X, D, m, n, R7 and R8 are as defined in the specification as estrogen receptor antagonists/degraders. The compound of Formula I can be used for the treatment of cancers mediated by estrogen receptors. (Formula I ).

Compounds with hydroxycarbonyl-halogenoalkyl side chain

The present invention provides a compound consisting of a moiety and a group chemically bonded to said moiety, wherein said moiety contains a compound having low activity following oral administration or its parent scaffold and said group has the followin