342900-89-4

Upstream product

• 914366-94-2 (E,4S,5R)-ethyl 5-hydroxy-4-methylhex-2-enoate 
• 100-52-7 benzaldehyde 
• 342900-78-1 ethyl (2E,4R,5R)-4-hydroxy-5-[(methylsulfonyl)oxy]-4-methylhex-2-enoate 
• 342900-76-9 ethyl (2E,4R,5R)-4,5-dihydroxy-4-methylhex-2-enoate 
• 149400-42-0 ethyl (2E,4E)-4-methylhexa-2,4-dienoate 
• 342900-84-9 ethyl (2E,4R,5S)-5-hydroxy-4-methylhex-2-enoate 
• 342900-82-7 ethyl (E)-3-[(2S,3S)-2,3-dimethyloxiran-2-yl]prop-2-enoate 
• 914366-87-3 (E)-ethyl 3-((4S,5R)-4,5-dimethyl-2-oxo-1,3-dioxolan-4-yl)acrylate 
• 914366-78-2 (E,4S,5R)-ethyl 4,5-dihydroxy-4-methylhex-2-enoate 
• 914367-01-4 (E)-ethyl 3-((2S,3R)-2,3-dimethyloxiran-2-yl)acrylate 
• 914366-77-1 (2E,4Z)-ethyl 4-methylhexa-2,4-dienoate 
• 19319-26-7 (Z)-2-methyl-2-buten-1-ol 

Relevant academic research and scientific papers

Asymmetric synthesis of the C(33)-C(37) fragment of amphotericin B

We have devised an expeditious, efficient, asymmetric synthesis of the C(33)-C(37) fragment of amphotericin B that proceeds in 14 steps and 16% overall yield from tiglic aldehyde ((E)-2-methylbut-2-enal) with complete stereocontrol. The route described he

De novo synthesis of 2-substituted syn-1,3-diols via an iterative asymmetric hydration strategy

(Chemical Equation Presented) The enantioselective syntheses of several protected 4-substituted syn-3,5-dihydroxy carboxylic esters have been achieved from the corresponding achiral (E,E)- or (E,Z)-1,3-dienoates. The route relies upon an enantio- and regi