34292-84-7

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 17 carbon (C) atoms, 13 hydrogen (H) atoms, 1 bromine (Br) atom, and 1 oxygen (O) atom.

Explanation

The compound has a ketone functional group (C=O), a pentadien-3-one backbone (a chain of five carbon atoms with alternating double and single bonds), and two substituted phenyl groups (aromatic rings with a hydrogen atom replaced by another group).

Explanation

The compound's structure consists of a pentadien-3-one backbone with a bromine atom attached to the 4th carbon of the phenyl group at the 1st position and a phenyl group at the 5th position.

Explanation

The compound is used in various fields, including organic synthesis and chemical research. It may also have potential applications in the development of pharmaceuticals and materials science due to its unique structure and reactivity.

Explanation

The compound's unique structure, with its pentadien-3-one backbone and substituted phenyl groups, contributes to its reactivity, making it an interesting target for further study and potential development in various fields.

Explanation

Although the exact physical state is not provided, compounds with similar structures and molecular weights are often found as solids or liquids at room temperature.

Explanation

Due to the presence of the carbon and hydrogen atoms in the molecule, the compound is likely to be soluble in organic solvents such as ethanol, methanol, or acetone.

Explanation

Many organic compounds, especially those with functional groups like ketones and aromatic rings, can be sensitive to heat, light, or moisture, which may affect their stability and reactivity. Proper storage and handling are necessary to maintain the compound's integrity.

Functional groups

Ketone, Pentadien-3-one backbone, Substituted phenyl groups

Structure

1,4-Pentadien-3-one backbone with a 4-bromophenyl group at the 1-position and a phenyl group at the 5-position

Applications

Organic synthesis, chemical research, potential pharmaceuticals, and materials science

Reactivity

Unique structure and reactivity

Physical state

Likely a solid or liquid at room temperature

Solubility

Likely soluble in organic solvents

Stability

May be sensitive to heat, light, or moisture

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 1896-62-4 (E)-benzalacetone 
• 129571-71-7 1-phenylpenta-1,4-dien-3-ol 
• 5467-74-3 4-Bromophenylboronic acid 

Downstream Products

• 79462-03-6 2-(4-Bromo-phenyl)-4-((E)-styryl)-2,3-dihydro-1H-benzo[b][1,4]diazepine 
• 79462-00-3 4-[(E)-2-(4-Bromo-phenyl)-vinyl]-2-phenyl-2,3-dihydro-1H-benzo[b][1,4]diazepine 

Relevant academic research and scientific papers

Oxygen as single oxidant for two steps: Base-free one-pot Pd(ii)-catalyzed alcohol oxidation & arylation to halogen-intact β-aryl α,β-enones

Using oxygen as the sole oxidant for two steps, we developed a new method to synthesize β-aryl α,β-enones by fine-tuning the Pd(ii)-catalyzed oxidation of allyl alcohol to subsequent arylation with arylboronic acids, arylboronic ester and aryltrifluoroborate salt. This one-pot green method does not require copper salt, base, and intermediate isolation. Halogen-bearing chalcones, dibenzylideneacetones and arylalkyl enones were synthesized in good yields. This journal is

Catalytic asymmetric synthesis of spirocyclic azlactones by a double Michael-addition approach

Spirocyclic azlactones are shown to be useful precursors of cyclic quaternary amino acids, such as the constrained cyclohexane analogues of phenylalanine. These compounds are of interest as building blocks for the synthesis of artificial peptide analogues with controlled folds in the peptide backbone. They were prepared in the present study by a step- and atom-economic catalytic asymmetric tandem approach, requiring two steps starting from N-benzoyl glycine and divinylketones. The key of this protocol is the enantioselective formation of the azlactone spirocycles, which involves a PdII-catalyzed double 1,4-addition of an in situ generated azlactone intermediate to the dienone (a formal [5+1] cycloaddition). As the catalyst, a planar chiral ferrocene bispalladacycle was used. Mechanistic studies suggest a monometallic reaction pathway. Although the diastereoselectivity was found to be moderate, the enantioselectivity is usually high for the formation of the azlactone spirocycles, which contain up to three contiguous stereocenters. Spectroscopic studies have shown that the spirocycles often prefer a twist over a chair conformation of the cyclohexanone moiety. A formal [5+1] cycloaddition of divinylketones and an in situ-generated glycine-derived azlactone was catalyzed by a chiral bis-palladacycle and provided highly enantioenriched, spirocyclic, masked amino acid products. The latter were used to synthesize biologically interesting constrained cyclohexane analogues of phenylalanine in just two steps (see scheme). Copyright