34315-37-2

Usage

Structure

Phenol group attached to a 2-(6-bromo-1,3-benzodioxol-5-yl)methylaminoethyl group

Components

Benzodioxole ring with bromine substitution, aminoethyl side chain

Potential applications

Medicinal chemistry, organic synthesis, drug development

Key features

Complex structure, structural elements commonly found in pharmaceutical compounds, potential building block for new drugs or chemical compounds

Upstream product

• 1609159-35-4 C₂₂H₃₂BrNO₃Si 
• 1609159-34-3 C₂₂H₃₄BrNO₃Si 
• 1609159-33-2 C₁₆H₂₀BrNO₃ 
• 1609159-31-0 C₁₆H₁₆BrNO₃ 
• 645388-77-8 (6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-[2-(4-methoxy-cyclohexa-1,4-dienyl)-ethyl]-amine 
• 15930-53-7 6-bromo-3,4-methylenedioxybenzaldehyde 
• 51-67-2 tyrosamine 

Downstream Products

• 213984-31-7 N-(6-Bromo-benzo[1,3]dioxol-5-ylmethyl)-2,2,2-trifluoro-N-[2-(4-hydroxy-phenyl)-ethyl]-acetamide 

Relevant academic research and scientific papers

Total synthesis of lycorine-type alkaloids by cyclopropyl ring-opening rearrangement

A practical method for the synthesis of lycorine-type alkaloids with cis-B/C ring structure has been developed. Based on the reactions of aminocyclization, palladium-mediated arylation and especially cyclopropyl ring-opening rearrangement, the synthesis o

Oxidative Intramolecular Phenolic Coupling Reaction Induced by a Hypervalent Iodine(III) Reagent: Leading to Galanthamine-Type Amaryllidaceae Alkaloids

By extending our oxidative phenol-coupling reactions using a hypervalent iodine(III) reagent, a versatile synthetic procedure for the galanthamine-type Amaryllidaceae alkaloids was accomplished. The first total synthesis of (±)-sanguinine and the total syntheses of (±)-galanthamine, (±)- narwedine, (±)-lycoramine, and (±)-norgalanthamine were also successfully carried out.