343254-49-9

Upstream product

• 144985-15-9 methyl 2-O-acetyl-3-O-allyl-4,6-O-benzylidene-1-thio-β-D-galactopyranoside 
• 244022-42-2 N-benzyloxycarbonyl-O-(3-O-acetyl-2-O-dibenzyloxyphosphinyl-β-D-xylopyranosyl)-L-serine benzyl ester 
• 343254-30-8 1,2,3,4-tetra-O-levulinoyl-α-D-xylopyranose 
• 343254-32-0 2,3,4-tri-O-levulinoyl-β-D-xylopyranosyl chloride 
• 244022-41-1 N-benzyloxycarbonyl-O-(3-O-acetyl-4-O-chloroacetyl-2-O-dibenzyloxyphosphinyl-β-D-xylopyranosyl)-L-serine benzyl ester 
• 244022-37-5 N-benzyloxycarbonyl-O-(2,3,4-tri-O-levulinoyl-β-D-xylopyranosyl)-L-serine benzyl ester 
• 244022-40-0 N-benzyloxycarbonyl-O-(3-O-acetyl-4-O-chloroacetyl-β-D-xylopyranosyl)-L-serine benzyl ester 
• 244022-39-7 N-benzyloxycarbonyl-O-(4-O-chloroacetyl-β-D-xylopyranosyl)-L-serine benzyl ester 
• 244022-38-6 N-benzyloxycarbonyl-O-β-D-xylopyranosyl-L-serine benzyl ester 
• 108549-23-1 Dibenzyl N,N-diisopropylphosphoramidite 
• 87-72-9 D-Xylose 

Downstream Products

• 343254-36-4 N-benzyloxycarbonyl-O-[O-(2-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl)-(1->4)-(3-O-acetyl-2-O-dibenzyloxyphosphinyl-β-D-xylopyranosyl)]-L-serine benzyl ester 

Relevant academic research and scientific papers

Synthesis of phosphorylated and sulfated glycosyl serines in the linkage region of the glycosaminoglycans

We synthesized novel acidic glycans having acidic groups located in the linkage region of the glycosaminoglycans (GAGs). The targeted compounds, β-D-Xyl(2P)-Ser (1), β-D-Gal(±6S)-(1→4)-β-D-Xyl(2P)-Ser (3 and 2), β-D-Gal(±6S)-(1→3)-β-D-Gal- (1→4)-β-D-Xyl(2P)-Ser (5 and 4), and β-D-Gal-(1→3)-β-D-Gal(6S)-(1→4)-β-D-Xyl(2P)-Ser (6) contain phosphate and/or sulfate at the specified positions. Some of them (3, 5, and 6) are the first synthesized examples of natural-type glycoconjugates that simultaneously possess phosphate and sulfate as well as carboxylic acid.