244022-39-7

Upstream product

• 244022-35-3 4-Oxo-pentanoic acid (3R,4S,5R)-2,4,5-tris-(4-oxo-pentanoyloxy)-tetrahydro-pyran-3-yl ester 
• 244022-36-4 4-Oxo-pentanoic acid (3R,4S,5R)-2-chloro-3,5-bis-(4-oxo-pentanoyloxy)-tetrahydro-pyran-4-yl ester 
• 343254-30-8 1,2,3,4-tetra-O-levulinoyl-α-D-xylopyranose 
• 343254-32-0 2,3,4-tri-O-levulinoyl-β-D-xylopyranosyl chloride 
• 244022-37-5 N-benzyloxycarbonyl-O-(2,3,4-tri-O-levulinoyl-β-D-xylopyranosyl)-L-serine benzyl ester 
• 87-72-9 D-Xylose 
• 79-04-9 chloroacetyl chloride 
• 244022-38-6 N-benzyloxycarbonyl-O-β-D-xylopyranosyl-L-serine benzyl ester 

Downstream Products

• 244022-42-2 N-benzyloxycarbonyl-O-(3-O-acetyl-2-O-dibenzyloxyphosphinyl-β-D-xylopyranosyl)-L-serine benzyl ester 
• 244022-41-1 N-benzyloxycarbonyl-O-(3-O-acetyl-4-O-chloroacetyl-2-O-dibenzyloxyphosphinyl-β-D-xylopyranosyl)-L-serine benzyl ester 
• 343254-36-4 N-benzyloxycarbonyl-O-[O-(2-O-acetyl-4,6-O-benzylidene-β-D-galactopyranosyl)-(1->4)-(3-O-acetyl-2-O-dibenzyloxyphosphinyl-β-D-xylopyranosyl)]-L-serine benzyl ester 
• 343254-49-9 N-benzyloxycarbonyl-O-{O-(2-O-acetyl-3-O-allyl-4,6-O-benzylidene-β-D-galactopyranosyl)-(1->4)-(3-O-acetyl-2-O-dibenzyloxyphosphinyl-β-D-xylopyranosyl)}-L-serine benzyl ester 
• 244022-40-0 N-benzyloxycarbonyl-O-(3-O-acetyl-4-O-chloroacetyl-β-D-xylopyranosyl)-L-serine benzyl ester 

Relevant academic research and scientific papers

Synthesis of phosphorylated and sulfated glycosyl serines in the linkage region of the glycosaminoglycans

We synthesized novel acidic glycans having acidic groups located in the linkage region of the glycosaminoglycans (GAGs). The targeted compounds, β-D-Xyl(2P)-Ser (1), β-D-Gal(±6S)-(1→4)-β-D-Xyl(2P)-Ser (3 and 2), β-D-Gal(±6S)-(1→3)-β-D-Gal- (1→4)-β-D-Xyl(2P)-Ser (5 and 4), and β-D-Gal-(1→3)-β-D-Gal(6S)-(1→4)-β-D-Xyl(2P)-Ser (6) contain phosphate and/or sulfate at the specified positions. Some of them (3, 5, and 6) are the first synthesized examples of natural-type glycoconjugates that simultaneously possess phosphate and sulfate as well as carboxylic acid.

Stereoselective syntheses of phosphorylated and sulfated glycosyl serines in glycosaminoglycan for biological probes

Phosphorylated glycosyl serines of glycosaminoglycan with/without sulfate: β-D-Xyl(2P)-Ser (1) and β-D-Gal(±6S)-(1→4)-β-D-Xyl(2P)-Ser (2, 3) were suitably designed for biological probes. These oligosaccharides were synthesized in a stereocontrolled manner.