34331-04-9

Basic information

• Product Name: 4-(5-acetoxy-7-hydroxy-4-oxo-4H-chromen-2-yl)phenylacetate
• Synonyms: 4-(5-acetoxy-7-hydroxy-4-oxo-4H-chromen-2-yl)phenylacetate
• CAS NO: 34331-04-9
• Molecular Weight: 354.316
• Mol File: 34331-04-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(5-acetoxy-7-hydroxy-4-oxo-4H-chromen-2-yl)phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-acetoxy-7-hydroxy-4-oxo-4H-chromen-2-yl)phenylacetate(34331-04-9)
• EPA Substance Registry System: 4-(5-acetoxy-7-hydroxy-4-oxo-4H-chromen-2-yl)phenylacetate(34331-04-9)

Safety Data

• Hazardous Substances Data: 34331-04-9(Hazardous Substances Data)

Upstream product

• 520-36-5 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 

Downstream Products

• 1610737-63-7 7-(tert-butoxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one 
• 1610737-74-0 5-hydroxy-2-(4-hydroxyphenyl)-7-morpholino-4H-chromen-4-one 
• 1104802-77-8 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl-4-methylbenzenesulfonate 
• 1610737-91-1 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-4-oxo-4Hchromen-7-yl4-methylbenzenesulfonate 
• 1610737-95-5 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-7-morpholino-4H-chromen-4-one 
• 1610737-52-4 4-(5-acetoxy-7-((4-fluorobenzyl)oxy)-4-oxo-4H-chromen-2-yl)phenyl acetate 
• 1610737-80-8 4-(5-acetoxy-7-(tert-butoxy)-4-oxo-4H-chromen-2-yl)phenyl acetate 
• 1610737-85-3 4-(5-acetoxy-4-oxo-7-(tosyloxy)-4H-chromen-2-yl)phenyl acetate 

Relevant articles and documents

Phosphoramidate protides of five flavones and their antiproliferative activity against HepG2 and L-O2 cell lines

A series of flavone-7-phosphoramidate derivatives were synthesized and tested for their antiproliferative activity in vitro against human hepatoma cell line HepG2 and human normal hepatic cell line L-O2. Compound 8d, 16d and 17d, incorporating the amino acid alanine, exhibited high inhibitory activity on HepG2 cell line with IC50 values of 9.0 μmol/L, 5.5 μmol/L and 6.6 μmol/L. The introduction of acyl groups played a pivotal role in the selective inhibition toward human hepatoma HepG2 cells, except for compound 8a, 9a and 16b. Compound 8d, 16d and 17d could significantly induce G2/M arrest in HepG2 cells. Specially, Compound 16d could lead early apoptosis in HepG2 cells.