1104802-77-8

Upstream product

• 1104802-64-3 4'-O-methoxymethyl-7-O-tosylapigenin 
• 1610737-85-3 4-(5-acetoxy-4-oxo-7-(tosyloxy)-4H-chromen-2-yl)phenyl acetate 
• 34331-04-9 4-(5-acetoxy-7-hydroxy-4-oxo-4H-chromen-2-yl)phenylacetate 
• 3316-46-9 apigenin triacetate 
• 520-36-5 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 

Downstream Products

• 1610737-74-0 5-hydroxy-2-(4-hydroxyphenyl)-7-morpholino-4H-chromen-4-one 
• 1610737-91-1 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-4-oxo-4Hchromen-7-yl4-methylbenzenesulfonate 
• 1610737-95-5 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-7-morpholino-4H-chromen-4-one 

Relevant academic research and scientific papers

Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75

HIV integrase (IN) is an essential enzyme for the viral replication. Currently, three IN inhibitors have been approved for treating HIV-1 infection. All three drugs selectively inhibit the strand transfer reaction by chelating a divalent metal ion in the

Synthesis of oriented anti-virus 7-O-substituted apigenins

7-O-Substituted apigenins were synthesized for searching anti-virus active compound. Using a commercially available naringenin as a starting material, 7-O-methylapigenin (1) and seven unnatural 7-0-substituted apigenin derivatives (13-19) were prepared via 4'-O-methoxymethylapigenin (5) as an intermediate.