343338-98-7Relevant academic research and scientific papers
Synthesis and SAR of heteroaryl-phenyl-substituted pyrazole derivatives as highly selective and potent canine COX-2 inhibitors
Cheng, Hengmiao,Lundy DeMello, Kristin M.,Li, Jin,Sakya, Subas M.,Ando, Kazuo,Kawamura,Kato, Tomoki,Rafka, Robert J.,Jaynes, Burton H.,Ziegler, Carl B.,Stevens, Rod,Lund, Lisa A.,Mann, Donald W.,Kilroy, Carolyn,Haven, Michelle L.,Nimz, Erik L.,Dutra, Jason K.,Li, Chao,Minich, Martha L.,Kolosko, Nicole L.,Petras, Carol,Silvia, Annette M.,Seibel, Scott B.
, p. 2076 - 2080 (2007/10/03)
The discovery of heteroaryl-phenyl-substituted pyrazole derivatives as canine selective COX-2 inhibitors is described. Structure-activity relationship (SAR) studies of this class of compounds led to the identification of compound 1 which demonstrated a ca
Heteroaryl phenyl pyrazole compounds as anti-inflammatory/analgesic agents
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Page/Page column 53, (2008/06/13)
This invention relates to a compound of the formula: or a pharmaceutically acceptable salt thereof, wherein A and R1are each an optionally substituted 5 to 6-membered heteroaryl, wherein the heteroaryl is optionally fused to a carbocyclic ring
