343372-31-6

Basic information

• Product Name: 7,7'-[[2-(HYDROXYMETHYL)-1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-7,13-DIYL]BIS(METHYLENE)]BIS[5-CHLORO-8-QUINOLINOL]
• Synonyms: 7,7'-[[2-(HYDROXYMETHYL)-1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-7,13-DIYL]BIS(METHYLENE)]BIS[5-CHLORO-8-QUINOLINOL]
• CAS NO: 343372-31-6
• Molecular Formula: C31H36Cl2N4O3S3
• Molecular Weight: 679.74354
• Mol File: 343372-31-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7,7'-[[2-(HYDROXYMETHYL)-1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-7,13-DIYL]BIS(METHYLENE)]BIS[5-CHLORO-8-QUINOLINOL](CAS DataBase Reference)
• NIST Chemistry Reference: 7,7'-[[2-(HYDROXYMETHYL)-1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-7,13-DIYL]BIS(METHYLENE)]BIS[5-CHLORO-8-QUINOLINOL](343372-31-6)
• EPA Substance Registry System: 7,7'-[[2-(HYDROXYMETHYL)-1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-7,13-DIYL]BIS(METHYLENE)]BIS[5-CHLORO-8-QUINOLINOL](343372-31-6)

Safety Data

• Hazardous Substances Data: 343372-31-6(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 130-16-5 5-Chloro-8-hydroxyquinoline 
• 122023-94-3 2-hydroxymethyl-7,14-diaza-1,4,10-trithiacyclopentadecane 
• 226211-71-8 bis<2-(α-chloroacetamido)ethyl> sulfide 
• 343372-27-0 3-hydroxymethyl-7,13-diaza-1,4,10-trithiacyclopentadecane-6,14-dione 

Relevant articles and documents

Bis-8-hydroxyquinoline-armed diazatrithia-15-crown-5 and diazatrithia-16-crown-5 ligands: Possible fluorophoric metal ion sensors

The synthesis and preliminary photophysical properties of a series of diazatrithia-15-crown-5 and diazatrithia-16-crown-5 ligands containing two 8-hydroxyquinoline sidearms are reported. The ligands were prepared by a two-step process. First, diazatrithiacrown ethers 11 and 12 were prepared by treating bis(α-chloroamide) 5 with various dimercaptans followed by reduction using a boron-THF complex. Hydroxymethyl-substituted macrocycle 12 was rearranged to hydroxy-substituted diazatrithia-16-crown-5 in refluxing aqueous HCl. Macrocyclic diamines 11-13 were converted to either 5-chloro-8-hydroxyquinolin-7-ylmethyl-substituted diazatrithiacrown ethers 14-16 by a Mannich aminomethylation reaction or to 8-hydroxyquinolin-2-ylmethyl-substituted diazatrithiacrown ethers 17-19 by reductive amination using 8-hydroxyquinoline-2-carboxaldehyde. Preliminary photophysical studies show that ligands 16 and 19 exhibit increased fluorescence in the presence of Zn2+, indicating that these ligands could be chemical sensors for Zn2+.