122023-94-3

Basic information

• Product Name: 1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-2-METHANOL
• Synonyms: 1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-2-METHANOL
• CAS NO: 122023-94-3
• Molecular Formula: C11H24N2OS3
• Molecular Weight: 296.51606
• Mol File: 122023-94-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-2-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-2-METHANOL(122023-94-3)
• EPA Substance Registry System: 1,4,10-TRITHIA-7,13-DIAZACYCLOPENTADECANE-2-METHANOL(122023-94-3)

Safety Data

• Hazardous Substances Data: 122023-94-3(Hazardous Substances Data)

Usage

Structure

Contains three sulfur atoms, two nitrogen atoms, and a methanol group in a macrocyclic structure.

Family

Thiacrown ether family

Applications

Potential applications in coordination chemistry and ion recognition.

Chelating ability

Can chelate metal ions due to the presence of thia and diaza units.

Solubility

Potential solubility in organic solvents due to the inclusion of a methanol group.

Further research

Warranted to fully understand its capabilities and potential uses.

Upstream product

• 226211-71-8 bis<2-(α-chloroacetamido)ethyl> sulfide 
• 343372-27-0 3-hydroxymethyl-7,13-diaza-1,4,10-trithiacyclopentadecane-6,14-dione 

Downstream Products

• 343372-29-2 3-hydroxy-8,14-diaza-1,5,11-trithiacyclohexadecane 
• 343372-31-6 8,13-bis(5-chloro-8-hydroxyquinolin-7-ylmethyl)-3-hydroxymethyl-8,13-diaza-1,3,10-trithiacyclopentadecane 

Relevant articles and documents

Bis-8-hydroxyquinoline-armed diazatrithia-15-crown-5 and diazatrithia-16-crown-5 ligands: Possible fluorophoric metal ion sensors

The synthesis and preliminary photophysical properties of a series of diazatrithia-15-crown-5 and diazatrithia-16-crown-5 ligands containing two 8-hydroxyquinoline sidearms are reported. The ligands were prepared by a two-step process. First, diazatrithiacrown ethers 11 and 12 were prepared by treating bis(α-chloroamide) 5 with various dimercaptans followed by reduction using a boron-THF complex. Hydroxymethyl-substituted macrocycle 12 was rearranged to hydroxy-substituted diazatrithia-16-crown-5 in refluxing aqueous HCl. Macrocyclic diamines 11-13 were converted to either 5-chloro-8-hydroxyquinolin-7-ylmethyl-substituted diazatrithiacrown ethers 14-16 by a Mannich aminomethylation reaction or to 8-hydroxyquinolin-2-ylmethyl-substituted diazatrithiacrown ethers 17-19 by reductive amination using 8-hydroxyquinoline-2-carboxaldehyde. Preliminary photophysical studies show that ligands 16 and 19 exhibit increased fluorescence in the presence of Zn2+, indicating that these ligands could be chemical sensors for Zn2+.