34356-36-0Relevant academic research and scientific papers
Bismuth triflate-catalyzed friedel-crafts acylations of sydnones
Mahoney, Jennifer,Turnbull, Kenneth,Cubberley, Mark
, p. 3220 - 3229 (2012/11/07)
Friedel-Crafts acylations of various 3-arylsydnones at the C4 position have been achieved in good yields using 4 equivalents of an alkyl anhydride and 25mol% each of bismuth triflate and lithium perchlorate in anhydrous acetonitrile at 95C. Acylations app
Design and synthesis of certain mesoionic sydnonyl styrylketones as potential nonsteroidal antiinflammatory agents
Deshpande, Shreenivas Ramachandrarao,Pai, Karkala Vasantakumar,Pai, Ranganath Sridhar
experimental part, p. 180 - 185 (2011/10/10)
In an attempt to develop effective and safer analgesic anti-inflammatory agents, nine compounds belonging to 4-[1-oxo-3-(substituted aryl)-2-propenyl]-3- (4-methoxyphenyl) sydnones, containing the structural features of mesoionic sydnone and styrylketone,
N-Bromosuccinimide (NBS) as Promoter for Acylation of Sydnones in the Presence of Acetic Anhydride under Neutral Conditions
Ghasemnejad-Bosra, Hassan,Haghdadi, Mina,Gholampour-Azizi, Issa
, p. 391 - 395 (2008/09/20)
Various 4 - acetyl sydnones (2) can be prepared by reaction of the corresponding 3-aryl sydnones (1) with acetic anhydride at ~110 °C promoted by N-Bromosuccinimide (NBS) as an effective reagent for acylation of sydnones under neutral conditions in satisf
1,3-Dibromo-5,5-dimethylhydantoin (DBH) as an efficient promoter for acetylation of 3-arylsydnones in the presence of acetic anhydride under neutral conditions
Azarifar, Davood,Bosra, Hassan Ghasemnejad,Tajbaksh, Mahmood
, p. 467 - 469 (2008/03/29)
(Chemical Equation Presented) 1,3-Dibromo-5,5-dimethylhydantoin (DBH) has been found to efficiently promote the conversion of various 3-arylsydnones to their 4-acetyl congeners in the presence of acetic anhydride under neutral conditions in satisfactory y
Synthesis and biological study of some novel 4-[5-(4,6-disubstituted-2- thiomethylpyrimidyl)-4'-amino-1,2,4- triazol-3'-yl] thioacetyl-3-arylsydnones
Kalluraya, Balakrishna,Lingappa,Nooji, Satheesh Rai
, p. 1393 - 1401 (2008/02/07)
A series of 4-[5-(4,6-disubstituted-2-thiomethyl pyrimidyl)-4'-amino-1,2-4- triazol-3'-yl]thioacetyl-3-arylsydnones 7a-i were synthesized by the reaction of 5-(4,6-disubstituted-2-thiomethylpyrimidyl)-4-amino-3-mercapto-1,2-4-triazoles 3 with 3-aryl-4-bromoacetyl sydnones 6 in an ethanol medium. The newly synthesized compounds 7a-i were screened for their antibacterial activity against E. coli and Serratia marcesens and for antibacterial activity against Aspergillus niger and Pencillium. Most of the tested compounds showed significant antifungal activity particularly against Pencillium at 10-g/mL concentration comparable with that of the standard drug Flukanazole.
