343596-01-0Relevant academic research and scientific papers
Effects of log P and phenyl ring conformation on the binding of 5- phenylhydantoins to the voltage-dependent sodium channel
Brown, Milton L.,Brown, George B.,Brouillette, Wayne J.
, p. 602 - 607 (1997)
Binding to the neuronal voltage-dependent sodium channel (NVSC) was evaluated for 12 5-phenylhydanteins which systematically varied either log P and/or 5-phenyl ring orientation. The linear correlation of log P with in vitro sodium channel binding activit
Synthesis of DL-hydroxybenzenamides as anticonvulsants
Meza-Toledo, Sergio E.,Yasutake-Kimoto, Liliana,Alcala-Renteria, Martha,Dominguez-Rodriguez, Miguel A.,Jaime-Rodriguez, Rodrigo,Nava-Arzaluz, Maria G.,Gutierrez-Laflor, Giovanna,Peralta-Cruz, Javier,Carvajal-Sandoval, Guillermo
, p. 105 - 110 (2008/09/19)
The anticonvulsant activity of some DL-hydroxybenzenamides is described. The following compounds from this series were prepared and tested: DL-2-hydroxy-2-(3′-bromophenyl)butyramide (4, CAS 620950-12-1), DL-2-hydroxy-2-(4′-bromophenyl)butyramide (5, CAS 6
