343614-08-4Relevant academic research and scientific papers
Enantioselective synthesis of 2- and 3-benzofuryl β-amino alcohols
Zaidlewicz, Marek,Chechlowska, Aldona,Prewysz-Kwinto, Andrzej,Wojtczak, Andrzej
, p. 569 - 577 (2007/10/03)
Enantioselective reduction of 2- and 3-bromoacetylbenzofurans with (-)-B-chlorodiisopinocampheylborane produced the corresponding bromohydrins which were transformed into (S)-(benzofuran-2-yl)oxirane of 70% ee and (S)-(benzofuran-3-yl)oxirane of 71% ee, respectively. The epoxides treated with primary alkylamines gave the corresponding (S)-1-(benzofuran-2- and -3-yl)-2-(alkylamino) ethanols.
