343846-36-6Relevant articles and documents
An efficient method of synthesizing optically pure N-Boc-4-bromo-N-methyl-1-tosyl-D-tryptophan methyl ester, a key intermediate in the synthesis of optically active ergot alkaloids
Yokoyama, Yuusaku,Osanai, Kumi,Mitsuhashi, Masaharu,Kondo, Kazuhiro,Murakami, Yasuoki
, p. 653 - 659 (2001)
Optically pure N-Boc-4-bromo-N-methyl-1-tosyl-D-tryptophan methyl ester (D-4), a key intermediate in the synthesis of optically active ergot alkaloids such as chanoclavine-I (7) and costaclavine (8), was prepared from N-acetyl-4-bromo-D-tryptophan (D-11) obtained from 4-bromoindole (9) and DL-serine (10) in two steps.