343846-39-9

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 343846-38-8 (R)-N-acetyl-4-bromo-1-tosyltryptophan methyl ester 
• 343846-36-6 (R)-N-acetyl-4-bromotryptophan methyl ester 
• 252026-08-7 N-acetyl-4-bromo-DL-tryptophan 
• 98-59-9 p-toluenesulfonyl chloride 
• 52488-36-5 4-bromo-1H-indole 

Downstream Products

• 343846-41-3 3-[4-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-2-tert-butoxycarbonylamino-propionic acid 
• 343846-42-4 N-(tert-butoxycarbonyl)-4-bromo-N-methyl-1-tosyl-D-tryptophan 

Relevant academic research and scientific papers

An efficient method of synthesizing optically pure N-Boc-4-bromo-N-methyl-1-tosyl-D-tryptophan methyl ester, a key intermediate in the synthesis of optically active ergot alkaloids

Optically pure N-Boc-4-bromo-N-methyl-1-tosyl-D-tryptophan methyl ester (D-4), a key intermediate in the synthesis of optically active ergot alkaloids such as chanoclavine-I (7) and costaclavine (8), was prepared from N-acetyl-4-bromo-D-tryptophan (D-11) obtained from 4-bromoindole (9) and DL-serine (10) in two steps.