34386-98-6Relevant academic research and scientific papers
Unusual radical addition on a heteroaromatic nitrogen. A convenient access to new pyrimidine derivatives
Laot, Yann,Petit, Laurent,Zard, Samir Z.
supporting information; experimental part, p. 5784 - 5786 (2010/09/05)
A radical generated on the side-chain of a 2- or 4-N-alkylamino-4,6- or 2,6-dichloropyrimidine can cyclise on the nitrogen or on the carbon of the pyrimidine ring depending on its position and on whether an acetyl or a Boc group is present on the extra-nuclear nitrogen.
ONE STEP SYNTHESIS OF 5-BROMO-2-CHLORO-6-HYDROXY-4-PYRIMIDINES, USEFUL INTERMEDIATES FOR THE PREPARATION OF PTERIDINE DERIVATIVES AND RELATED ANALOGUES
Botta, Maurizio,Saladino, Raffaele,Nicoletti, Rosario
, p. 729 - 737 (2007/10/02)
A simple synthesis of pteridine derivatives (12) and (13), 5-oxapteridines (10a-c) and 5-thiapteridine (15) via cyclization of the highly functionalized pyrimidinones (8 a-c) is reported.
