343941-51-5

Basic information

• Product Name: 2-ethoxy-2-methoxy-1-phenylethanol
• Synonyms: 2-ethoxy-2-methoxy-1-phenylethanol
• CAS NO: 343941-51-5
• Molecular Weight: 196.246
• Mol File: 343941-51-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-ethoxy-2-methoxy-1-phenylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxy-2-methoxy-1-phenylethanol(343941-51-5)
• EPA Substance Registry System: 2-ethoxy-2-methoxy-1-phenylethanol(343941-51-5)

Safety Data

• Hazardous Substances Data: 343941-51-5(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 67-56-1 methanol 
• 13294-31-0 (Z)-(2-ethoxyethenyl)benzene 

Relevant articles and documents

ELABORATION OF THE ACYL LIGAND IN (η5-C5H5)Fe(CO)(PPh3)(COCH2OCH3)

Deprotonation of the complex (η5C5H5)Fe(CO)(PPh3)(COCH2OCH3) leads to anion 7 which can be alkylated stereoselectively to products of RFeRα/SFeSα configuration.Reaction of 7 with acetaldehyde or benzaldehyde are not stereoselective and yield four stereoisomeric products 16-19 or 20-23, respectively.Exchange of the lithium cation for diethylaluminium or divalent tin cations improves the stereoselectivity in reaction of 7 with carbonyl compounds.Reaction of 7 with acetone leads to product 24 of the RFeSα/SFeRα configuration.Decomplexation of 20with NBS and methanol is connected with decarbonylation and leads to mandelaldehyde dimethyl acetal.With other alcohols mixtures of diastereoisomeric mixed acetals are formed.Similar results are achieved with other mild oxidizing reagents as cerium ammonium nitrate or selenium dioxide.Oxidation of 20 with m-chloroperoxybenzoic acid leads mainly to one of the diastereoisomeric acetals although in a low yield.Decomplexation of 15 with NBS and ethanol leads to mixed acetal 29.