343975-49-5Relevant academic research and scientific papers
Synthesis of 2-arylbenzothiazoles by DDQ-promoted cyclization of thioformanilides; a solution-phase strategy for library synthesis
Bose, D. Subhas,Idrees,Srikanth, Bingi
, p. 819 - 823 (2007/12/29)
Several substituted benzothiazoles were synthesized by the intramolecular cyclization of thioformanilides using 2,6-dichloro-3,5-dicyano-1,4-benzoquinone (DDQ) in dichloromethane at ambient temperature in high yields. The resulting 2-arylbenzothiazoles we
A convenient access to substituted benzothiazole scaffolds via intramolecular cyclization of thioformanilides
Bose, D. Subhas,Idrees
, p. 669 - 672 (2007/10/03)
A new and practical method has been developed for the synthesis of substituted benzothiazoles via the intramolecular cyclization of thioformanilides using DDQ in CH2Cl2 at ambient temperature. The reaction proceeds in high yields via
Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles
Hutchinson,Chua,Browne,Trapani,Bradshaw,Westwell,Stevens
, p. 1446 - 1455 (2007/10/03)
Synthetic routes to a series of mono- and difluorinated 2-(4-amino-3-substituted-phenyl)benzothiazoles have been devised. Whereas mixtures of regioisomeric 5- and 7-fluorobenzothiazoles were formed from the established Jacobsen cyclization of precursor 3-
