34399-78-5

Basic information

• Product Name: methyl 3-(3-oxocyclopentyl)propanoate
• Synonyms: Cyclopentanepropanoic acid, 3-oxo-, methyl ester; Methyl 3-(3-oxocyclopentyl)propanoate
• CAS NO: 34399-78-5
• Molecular Formula: C₉H₁₄O₃
• Molecular Weight: 170.2057
• Mol File: 34399-78-5.mol

Chemical Properties

• Boiling Point: 245.4°C at 760 mmHg
• Flash Point: 101.8°C
• Density: 1.068g/cm³
• Vapor Pressure: 0.0288mmHg at 25°C
• Refractive Index: 1.459
• CAS DataBase Reference: methyl 3-(3-oxocyclopentyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(3-oxocyclopentyl)propanoate(34399-78-5)
• EPA Substance Registry System: methyl 3-(3-oxocyclopentyl)propanoate(34399-78-5)

Safety Data

• Hazardous Substances Data: 34399-78-5(Hazardous Substances Data)

Usage

Uses

Used in Flavoring Agents:
Methyl 3-(3-oxocyclopentyl)propanoate is used as a flavoring agent in the food industry. Its fruity odor makes it suitable for enhancing the taste and aroma of various food products.
Used in Fragrance:
In the cosmetic and personal care products industry, methyl 3-(3-oxocyclopentyl)propanoate is used as a fragrance. Its pleasant scent adds a desirable aroma to these products, making them more appealing to consumers.
Used in Pharmaceutical Manufacturing:
Methyl 3-(3-oxocyclopentyl)propanoate is utilized in the manufacturing of pharmaceuticals. Its chemical properties make it a valuable component in the production of certain medications.
Used as a Solvent:
In various chemical processes, methyl 3-(3-oxocyclopentyl)propanoate serves as a solvent. Its ability to dissolve other substances makes it useful in a range of applications within the chemical industry.

Upstream product

• 186581-53-3 diazomethane 
• 34399-77-4 3-(3-Oxocyclopentanyl)propanoic acid 
• 930-30-3 cyclopent-2-enone 
• 5009-28-9 cyclopropanone methyl hemiacetal 
• 69391-83-9 3-(3-oxo-cyclopent-1-enyl)-propionic acid methyl ester 
• 34399-76-3 3-(3'-hydroxypropyl)cyclopentan-1-one 
• 67-56-1 methanol 
• 90953-74-5 bicyclo<3.3.0>octane-2,8-dione 

Relevant articles and documents

Asymmetric 1,4-reductions of and 1,4-additions to enoates and related systems

One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, th

The mechanism of the photochemical cycloaddition reaction between 2-cyclopentenone and polar alkenes: Trapping of triplet 1,4-biradical intermediates with hydrogen selenide

The regiochemistry of the photochemical cycloaddition reaction between 2-cyclopentenone and the polar alkenes 1,1-difluoroethene and methyl acrylate has been investigated. With 1,1-difluoroethene the major cycloaddition product is a cyclobutane adduct possessing head-to-tail regiochemistry; with methyl acrylate the reaction is non-regioselective and a 46.5:53.5 ratio of head-to-head and head-to-tail cyclobutane regioisomers is obtained. These regiochemical outcomes are not those predicted by the Corey - de Mayo mechanism conventionally used to describe the enone - alkene photocycloaddition reaction. The triplet 1,4-biradicals implicated as intermediates in the photocycloaddition reaction between 2-cyclopentenone and the polar alkenes methyl acrylate and ethyl vinyl ether have been trapped quantitatively using hydrogen selenide as a hydrogen atom donor. The structures of the trapped products have been determined and hence the structures of their biradical precursors have been inferred. The yields of the trapped biradicals indicate that in both reactions the product distribution is controlled by the extent to which each of the isomeric biradical intermediates closes to products in competition with fragmentation to its ground state precursors. The product distribution does not reflect the relative rates of formation (and hence the relative amounts) of the isomeric biradical intermediates formed in each reaction. This conclusion is inconsistent with the long held idea that an oriented exciplex intermediate controls the reaction regiochemistry by favoring the formation of some biradicals over others. The structures of the biradical intermediates also reveal that both the 2-position and the 3-position of the enone are involved in forming the first bond to the alkene; with ethyl vinyl ether this bond is to the less substituted end of the alkene exclusively, while with methyl acrylate no selectivity in the site of initial bonding is observed.

REGIOCONTROL BY ELECTRON WITHDRAWING GROUPS IN THE Rh-CATALYZED C-H INSERTION OF α-DIAZOKETONES

It is possible to control the regiochemistry of the Rh-catalyzed insertion of α-diazoketones into C-H bonds by taking advantage of the greatly reduced rate of insertion into methylenes which are α or β to a carbonyl function.The 2-carboxyethyl group is especially useful for this purpose because it can be transformed eventually into a variety of other substituents.