34403-38-8

Basic information

• Product Name: 2-Pyridin-3-ylMethyl-isoindole-1,3-dione
• Synonyms: 2-Pyridin-3-ylMethyl-isoindole-1,3-dione;2-(Pyridin-3-ylMethyl)isoindoline-1,3-dione
• CAS NO: 34403-38-8
• Molecular Formula: C₁₄H₁₀N₂O₂
• Molecular Weight: 238.2414
• Mol File: 34403-38-8.mol
• Article Data: 8

Chemical Properties

• Melting Point: 156-157 °C
• Boiling Point: 423.7±28.0 °C(Predicted)
• Appearance: /
• Density: 1.368±0.06 g/cm3(Predicted)
• PKA: 4.75±0.10(Predicted)
• CAS DataBase Reference: 2-Pyridin-3-ylMethyl-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridin-3-ylMethyl-isoindole-1,3-dione(34403-38-8)
• EPA Substance Registry System: 2-Pyridin-3-ylMethyl-isoindole-1,3-dione(34403-38-8)

Safety Data

• Hazardous Substances Data: 34403-38-8(Hazardous Substances Data)

Upstream product

• 3731-52-0 3-Aminomethylpyridine 
• 612-14-6 phthalyl alcohol 
• 85-44-9 phthalic anhydride 

Downstream Products

• 3731-52-0 3-Aminomethylpyridine 
• 612-14-6 phthalyl alcohol 
• 1191083-51-8 [Au(PPh₃)(3-aminomethyl-N-phthalimidopyridine)](OTf) 

Relevant articles and documents

Synthesis, structure, and two polymorphs of 4-((1,3-Dioxoisoindolin-2-yl) methyl)-1-methoxypyridinium tetrafluoroborate

4-((1,3-Dioxoisoindolin-2-yl)methyl)-1-methoxypyridinium tetrafluoroborate, C15H13BF4N2O3, 1, was obtained by alkylation of the corresponding N-oxide and has been characterized by 1H and s

Direct Synthesis of Cyclic Imides from Carboxylic Anhydrides and Amines by Nb2O5 as a Water-Tolerant Lewis Acid Catalyst

In the 20 types of heterogeneous and homogenous catalysts screened, Nb2O5 showed the highest activity for the synthesis of N-phenylsuccinimide by dehydrative condensation of succinic anhydride and aniline. Nb2O5 was used in the direct imidation of a wide range of carboxylic anhydrides with NH3 or amines with various functional groups and could be reused. Kinetic studies showed that the Lewis acid Nb2O5 catalyst was more water tolerant than both the Lewis acidic oxide TiO2 and the homogeneous Lewis acid ZrCl4, which resulted in higher yields of imides through the use of Nb2O5. Int-imidation tactics: A general method for the direct synthesis of cyclic imides from cyclic anhydrides with amines (or ammonia) under solvent-free conditions is reported. Kinetic studies indicate that the Lewis acid sites of Nb2O5 are highly water tolerant, which results in high catalytic activity for imidation even in the presence of water formed during the reaction. The catalyst can be recovered and reused four times without a marked decrease in yield.

Synthesis of cyclic imides from simple diols

There's something imide so strong: Cyclic imides were synthesized from simple diols with primary amines in a single step using an in-situ-generated ruthenium catalytic system. The atom-economical and operatively simple syntheses of succinimides, phthalimides, and glutarimides, which are important building blocks in natural products and drugs, was also demonstrated. Copyright