344403-81-2

Upstream product

• 1078691-95-8 (+)-D-glucosamine hydrochloride 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 171032-74-9 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-glucopyranose 
• 282526-04-9 methyl 2-azido-2-deoxy-1-thio-β-D-glucopyranoside 
• 146934-27-2 Methyl 2-azido-2-deoxy-3,4,6-tri-O-acetyl-1-thio-α-D-glucopyranoside 

Downstream Products

• 1271131-92-0 4-(N-benzyloxycarbonylamino)-2-azido-3-O-chloroacetyl-2,4,6-trideoxy-β-D-galactopyranose 
• 501088-46-6 tert-butyldiphenylsilyl 2-azido-2-deoxy-β-D-glucopyranoside 
• 1384556-75-5 2-trichloromethyl-4,5-dihydro-(2-azido-2,4,6-trideoxy-1-O-tert-butyldiphenylsilyl-β-D-allopyranoso)[3,4-d]-1,3-oxazole 
• 1384556-72-2 2-trichloromethyl-4,5-dihydro-(2-azido-2,4,6-trideoxy-1-O-tert-butyldiphenylsilyl-β-D-galactopyranoso)[4,3-d]-1,3-oxazole 

Relevant academic research and scientific papers

One-Step TEMPO-Catalyzed and Water-Mediated Stereoselective Conversion of Glycals into 2-Azido-2-deoxysugars with a PIFA-Trimethylsilyl Azide Reagent System

An unprecedented water-mediated and TEMPO-catalyzed, one-step, highly regiospecific and stereoselective functionalization of glycals to 2-azido-2-deoxysugars has been developed using a PIFA-Me3SiN3 reagent system in the presence of B

Synthetic heparin pentasaccharides

Preparation and use of synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides useful for the preparation of synthetic heparinoids.

Synthesis of novel, fluorescently tagged analogs of glycosylphosphatidylinositol (GPI) anchors

Glycosylphosphatidylinositol (GPI) anchors are a group of complex glycolipids that attach extracellular proteins and glycoproteins to the eukaryotic cell outer membrane. To better understand GPI anchorage, it is necessary to have access to homogeneous, structurally defined, and functionalized GPIs and GPI analogs. In this regard, chemical synthesis is necessary, as GPI anchors are rather scarce and heterogeneous in natural sources. Three GPI analogs with phosphoglycerolipids linked to the pseudodisaccharide core and their fluorescein conjugates were prepared in this work as a small tool set useful for probing how the lipid composition and carbohydrate anomeric configuration may affect the properties of GPI anchors.

Multigram-scale synthesis of an orthogonally protected 2-acetamido-4-amino- 2,4,6-trideoxy-d-galactose (AAT) building block

Reported is the gram-scale synthesis of tert-butyldiphenylsilyl 4-(N-benzyloxycarbonyl)-amino-2-azido-2,4,6-trideoxy-β-d-galactopyranoside, which represents an orthogonally protected 2,4-diamino-d-fucose building block, a common constituent of various zwi