344460-45-3

Upstream product

• 369-34-6 3,4-difluoronitrobenzene 
• 344460-43-1 [4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-carbamic acid benzyl ester 
• 147740-02-1 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine hydrochloride salt 
• 344460-40-8 6,7-Dihydro-6-(2-fluoro-4-nitrophenyl)-5H-pyrrolo[3,4-b]pyridine 
• 344460-41-9 6,7-Dihydro-6-(2-fluoro-4-aminophenyl)-5H-pyrrolo[3,4-b]pyridine 
• 147740-01-0 ethyl 5,7-dihydro-6H-pyrrolo[3,4-b]pyridine-6-carboxylate 
• 124-63-0 methanesulfonyl chloride 
• 344459-52-5 (5R)-3-[4-(5,7-Dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone 

Downstream Products

• 906480-79-3 1-{3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-1H-pyridin-2-one 
• 344459-66-1 3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-5-([1,2,5]thiadiazol-3-yloxymethyl)-oxazolidin-2-one 
• 906480-78-2 6-{3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethoxy}-nicotinonitrile 
• 344459-63-8 3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-5-(pyrazin-2-yloxymethyl)-oxazolidin-2-one 
• 344459-80-9 N-{3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-methanesulfonamide 
• 344459-74-1 {3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-carbamic acid methyl ester 
• 344459-68-3 N-{3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-propionamide 
• 344459-70-7 cyclopropanecarboxylic acid {3-[4-(5,7-dihydro-pyrrolo[3,4-b]pyridin-6-yl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-amide 

Relevant academic research and scientific papers

Antibacterial activity of pyrrolopyridine-substituted oxazolidinones: synthesis and in vitro SAR of various C-5 acetamide replacements

A series of pyrrolopyridine-substituted oxazolidinones containing various C-5 acetamide isosteres was synthesized and the structure-antibacterial activity relationships determined against a representative panel of susceptible and resistant Gram-positive b

Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones

A novel series of oxazolidinones containing a pyrroloaryl substituent was synthesized and screened against a representative panel of susceptible and resistant Gram-positive bacteria. Several members of this series were found to have antibacterial activity comparable to or better than linezolid.