344465-96-9

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 344465-95-8 5-(2-methanesulfonyl-pyrimidin-4-yl)-6-(3-trifluoromethyl-phenyl)-4,5-dihydro-2H-pyridazin-3-one 
• 344465-94-7 5-(2-Methylsulfanylpyrimidin-4-yl)-6-(3-trifluoromethylphenyl)-4,5-dihydro-2H-pyridazin-3-one 
• 344465-93-6 3-(2-methylsulfanyl-pyrimidin-4-yl)-4-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid 
• 344465-92-5 3-(2-methylsulfanyl-pyrimidin-4-yl)-4-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid methyl ester 
• 200801-88-3 2-(2-Methylsulfanylpyrimidin-4-yl)-1-(3-trifluoromethylphenyl)ethanone 

Downstream Products

• 344465-98-1 (s)-6-Chloro-4-[2-(1-phenylethylamino)pyrimidin-4-yl]-3-(3-trifluoromethyl-phenyl)pyridazine 
• 344465-97-0 5-[2-((S)-1-Phenyl-ethylamino)-pyrimidin-4-yl]-6-(3-trifluoromethyl-phenyl)-pyridazin-3-ol 

Relevant academic research and scientific papers

Pyridazine based inhibitors of p38 MAPK

Trisubstituted pyridazines were synthesized and evaluated as in vitro inhibitors of p38 MAPK. The most active isomers were those possessing an aryl group α and a heteroaryl group β relative to the nitrogen atom in the 2-position of the central pyridazine.