3446-05-7

Usage

Derivative of

hydroquinone

Industrial applications

a. Synthesis of pharmaceuticals
b. Synthesis of agrochemicals
c. Synthesis of other organic compounds

Additional uses

a. Production of dyes
b. Production of pigments
c. Production of antioxidants

Physical state

solid, white powder

Solubility

soluble in water and organic solvents

Health hazards

potential irritant to skin, eyes, and respiratory system

Environmental impact

toxic effects on aquatic organisms, potential environmental pollutant

InChI:InChI=1/C7H7ClO2/c1-4-2-5(9)3-6(10)7(4)8/h2-3,9-10H,1H3

Upstream product

• 2524-37-0 ethyl orselinate 
• 3187-58-4 methyl orsellinate 
• 83324-60-1 4,6-dichloro-5-methyl-1,3-cyclohexanedione 
• 57074-23-4 ethyl 5-chloro-orsellinate 
• 504-15-4 orcinol 

Downstream Products

• 68048-11-3 3,5-dibenzyloxy-2-chlorotoluene 
• 69769-50-2 methyl 3-chloro-6-(3,5-dichloro-2-hydroxy-4-methoxy-6-methylphenoxy)-4-hydroxy-2-methylbenzoate 
• 69709-91-7 3,5,5'-trichloro-2,2',4,4'-tetrahydroxy-6,6'-dimethylbenzophenone 
• 69709-89-3 3,5,5'-trichloro-2,2',4'-trihydroxy-4-methoxy-6,6'-dimethylbenzophenone 
• 78135-51-0 3-chloro-6-(3,5-dichloro-2-hydroxy-4-methoxy-6-methylphenoxy)-4-hydroxy-2-methylbenzoic acid 
• 78135-36-1 2,2',4'-tribenzyloxy-3,5,5'-trichloro-4-methoxy-6,6'-dimethylbenzophenone 
• 78135-39-4 2,2',4,4'-tetrabenzyloxy-3,5,5'-trichloro-6,6'-dimethylbenzophenone 
• 68048-24-8 2,4,4',6,6'-Pentabenzyloxy-3,3'-dichlor-2'-methylbenzophenon 
• 68048-32-8 3,3'-Dichlor-2,4,4',6,6'-pentahydroxy-2'-methyl-benzophenon 
• 101292-45-9 1,5-diacetoxy-2-chloro-4-diacetoxymethyl-3-methyl-benzene 
• 112990-33-7 3-chloro-4,6-bis-methoxycarbonyloxy-2-methyl-benzaldehyde 
• 30448-89-6 3-chloro-4,6-dihydroxy-2-methylbenzoic acid 
• 83324-59-8 3-chloro-4,6-dihydroxy-2-methyl-benzaldehyde 
• 861071-95-6 4-chloro-5-methyl-6-nitroso-resorcinol 

Relevant academic research and scientific papers

Synthesis of chloro-substituted 6H-dibenzo[b,d]pyran-6-one natural products, graphislactone G, and palmariols A and B

A palladium-mediated intramolecular aryl–aryl coupling reaction was applied to the total synthesis of the bioactive natural products, graphislactone G (1), and palmariols A (2) and B (3), which possess an unusual chloro-subsutituent on the 6H-dibenzo[b,d]

Scensidin, a New Depsidone from the Lichen Buellia canescens (Dicks.) De Not

The biogenetically favored constitution (4) for scensidin isolated from Buellia canescens has been established by total synthesis.Intramolecular oxidative coupling of the tetrahydroxybenzophenone (22) yields the grisadienedione (23) which, by thermal isomerisation (23) -> (25) followed by methylation, yields scensidin (4).Alternatively, methylation of the grisadienedione (23) followed by thermal isomerisation also yields scensidin.The transformation of the grisadienone (26) into the dibenzofuran (28) occurs both thermally and photochemically.

A GENERAL SYNTHETIC METHOD FOR PRENYLATED PHENOLS OF MICROBIAL ORIGIN

Prenylated phenols with a fully substituted benzene ring, such as colletochlorins A and B, were synthesized by first prenylating 1,5-dimethoxy-3-methyl-1,4-cyclohexadiene and then effecting the aromatization of the prenylated product.

Depsidone Synthesis. Part 16. Benzophenone-Grisa-3',5'-diene-2',3-dione-depsidone Interconversion: a New Theory of Depsidone Biosynthesis

The synthesis of a number of grisa-3',5'-diene-2',3-diones by oxidative coupling of substituted 2,2'-dihydroxy-4-methoxybenzophenones is described.The rearrangement of these grisadienediones to depsidones under basic, acidic, and thermal conditions is des