3187-58-4

Basic information

• Product Name: METHYL ORSELLINATE
• Synonyms: Orsellinic acid methyl;6-Methyl-β-resorcylic acid methyl;Methyl o-orsellinate;o-Orsellinic acid methyl
• CAS NO: 3187-58-4
• Molecular Formula: C₉H₁₀O₄
• Molecular Weight: 182.18
• Product Categories: Aromatic Esters
• Mol File: 3187-58-4.mol
• Article Data: 49

Chemical Properties

• Melting Point: 141-142℃
• Boiling Point: 339℃
• Flash Point: 138℃
• Appearance: /
• Density: 1.296
• Vapor Pressure: 4.8E-05mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: 2-8°C
• PKA: 8.27±0.23(Predicted)
• CAS DataBase Reference: METHYL ORSELLINATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL ORSELLINATE(3187-58-4)
• EPA Substance Registry System: METHYL ORSELLINATE(3187-58-4)

Safety Data

• Hazardous Substances Data: 3187-58-4(Hazardous Substances Data)

Usage

Uses

Methyl 2,4-Dihydroxy-6-methylbenzoate is a useful synthetic intermediate in the synthesis of Grifolic Acid (G786500); a selective partial GPR120 agonist. Grifolic Acid induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40.

InChI:InChI=1/C9H10O4/c1-5-3-6(10)4-7(11)8(5)9(12)13-2/h3-4,10-11H,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 60-29-7 diethyl ether 
• 480-64-8 orsellinic acid 
• 67-56-1 methanol 
• 106-99-0 buta-1,3-diene 
• 548-89-0 gyrophoric acid 
• 480-56-8 lecanoric acid 
• 30666-92-3 umbilicaric acid 
• 674-82-8 4-methyleneoxetan-2-one 
• 74590-73-1 1,3-bis(trimethylsiloxy)-1-methoxybuta-1,3-diene 
• 77-78-1 dimethyl sulfate 
• 105-45-3 acetoacetic acid methyl ester 
• 860752-66-5 2,4-bis-methoxycarbonyloxy-6-methyl-benzoic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 520-43-4 2-hydroxy-4-methoxy-6-methyl-benzoic acid methyl ester 
• 300719-60-2 Methyl 2,4-bis(benzyloxymethoxy)-6-methylbenzoate 
• 705931-13-1 2,7-dimethyl-5-hydroxy-2-(4-methylpent-3-enyl)-2H-1-benzopyran-6-carboxylic acid 
• 118607-98-0 methyl (E)-2,4-di(methylsulfonyl)-6-methyl-3-<(3-methyl-6-methylsulfonyl)-2-hexenyl>-benzoate 
• 118608-03-0 methyl (E)-2,4-di(methoxymethoxy)-6-methyl-3-<3-methyl-6-<5-(2-methyl-1-propenyl)-3-furanyl>-2-hexenyl>-benzoate 
• 118607-99-1 methyl (E)-2,4-di(methylsulfonyl)-6-methyl-3-<(6-iodo-3-methyl)-2-hexenyl>-benzoate 
• 118608-02-9 methyl (E)-2,4-di(methoxymethoxy)-6-methyl-3-<3-methyl-6-(furanyl-5-carboxaldehyde)-2-hexenyl>-benzoate 
• 118607-95-7 methyl (E)-2,4-di(methoxymethoxy)-6-methyl-3<<3-methyl-6-(methylsulfonyl)>-2-hexenyl>-benzoate 
• 118649-30-2 methyl (E)-2,4-di(methoxymethoxy)-6-methyl-3<(6-O-tert-butyldimethylsilyl-3-methyl)-2-hexenyl>-benzoate 
• 6110-37-8 methyl 2,4-dimethoxy-6-methylbenzoate 
• 1007852-66-5 methyl 4-hydroxy-2-methyl-6-(trifluoromethylsulfonyloxy)benzoate 
• 1007852-69-8 methyl 2-hydroxy-6-methyl-4-(trifluoromethylsulfonyloxy)benzoate 
• 58061-98-6 methyl 2,4-bis(benzyloxy)-6-methylbenzoate 
• 118608-04-1 methyl (E)-4-hydroxy-2-methoxymethoxy-6-methyl-3<3-methyl-6-<5-(2-methyl-1-propenyl)-3-furanyl>-2-hexenyl>-benzoate 

Relevant articles and documents

Chemical Studies on the Lichen. I. The Structure of Isolecanoric Acid, a New ortho-Depside Isolated from Parmelia tinctorum Despr.

A new ortho-depside, isolecanoric acid was isolated from Parmelia tinctorum Despr. and 2-(2,4-dihydroxy-6-methylbenzoyloxy)-4-hydroxy-6-methylbenzoic acid was assigned to this substance from studies on the hydrolysis products and from analyses of the 1H and 13C NMR spectra.This substance is the first ortho-depside isolated from the genus Lichen.

Photolytic Studies on the Generation and Trapping of 6-Oxomethylidenecyclohexa-2,4-diene-1-one Derivatives with Various Nucleophiles

α-Oxoketenes and cyclohexadiene α-oxoketenes are reactive intermediates, particularly the latter due to their high re-aromatization potential. In this communication, we report photolytic studies on the generation of such species from 4-OMe and 4-OMOM protected resorcylate dioxinones and their trapping to give resorcylate esters and amides as well as the formation of adducts with enol-ethers as trapping reagents.

CANNABIDIOL-TYPE CANNABINOID COMPOUND

The present invention relates to a cannabidiol (CBD) type cannabinoid compound for use as a medicament. The CBD-type cannabinoid, cannabidiol-C1 (CBD-C1), is a naturally occurring cannabinoid that can be found in minor quantities in the cannabis plant. Furthermore, the 5 cannabinoid can be produced by synthetic means and a method for the production of CBD-C1 is described herein. In addition, disclosed herein are data which demonstrate the efficacy of CBD-C1 in models of disease.