3446-77-3

Usage

Uses

Used in Pharmaceutical Research:
2,4-dimethoxy-N-(4-methoxyphenyl)benzenemethanamine is used as a research compound for its potential therapeutic applications. Its stimulant effects on the central nervous system make it a subject of interest for the development of new medications targeting various neurological and psychiatric disorders.
Used in Drug Development:
In the pharmaceutical industry, 2,4-dimethoxy-N-(4-methoxyphenyl)benzenemethanamine is used as a starting material or intermediate in the synthesis of other active pharmaceutical ingredients. Its unique structural features allow for the exploration of novel drug candidates with improved efficacy and reduced side effects.
Used in Neurological Disorders Treatment:
2,4-dimethoxy-N-(4-methoxyphenyl)benzenemethanamine is used as a potential therapeutic agent for the treatment of neurological disorders. Its stimulant properties may offer benefits in managing symptoms associated with conditions such as attention deficit hyperactivity disorder (ADHD), narcolepsy, and certain mood disorders.
Used in Central Nervous System Stimulants:
In the field of medicine, 2,4-dimethoxy-N-(4-methoxyphenyl)benzenemethanamine is used as a central nervous system stimulant. Its ability to increase alertness, focus, and energy levels makes it a candidate for the treatment of fatigue and cognitive impairment in various medical conditions.

Upstream product

• 123794-61-6 N-(2,4-dimethoxybenzylidene)-4-methoxyaniline 
• 104-94-9 4-methoxy-aniline 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Downstream Products

• 1537188-68-3 ethyl 2-((2,4-dimethoxybenzyl)(4-methoxyphenyl)carbamoyl)-3-hydroxybut-2-enoate 
• 1537188-67-2 C₂₃H₂₇NO₇ 
• 1537188-66-1 ethyl 3-((2,4-dimethoxybenzyl)(4-methoxyphenyl)amino)-3-oxopropanoate 
• 1370018-46-4 N-(2,4-dimethoxybenzyl)-N-(4-methoxyphenyl)-1-methyl-2-oxopyrrolidine-3-carboxamide 
• 1370018-20-4 tert-butyl 3-((2,4-dimethoxybenzyl)(4-methoxyphenyl)carbamoyl)-2-oxopiperidine-1-carboxylate 
• 891186-77-9 3-allyl-1-(2,4-dimethoxy-benzyl)-5-methoxy-2-oxo-2,3-dihydro-1-H-indole-3-carboxylic acid ethyl ester 
• 891186-79-1 1-(2,4-dimethoxy-benzyl)-5-methoxy-2-oxo-3-(2-oxo-ethyl)-2,3-dihydro-1H-indole-3-carboxylic acid ethyl ester 
• 891186-81-5 (S)-1-(2,4-dimethoxybenzyl)-5-methoxy-1'-methylspiro[indoline-3,3'-pyrrolidine]-2,2'-dione 
• 891186-73-5 ethyl 2-diazo-3-(N-(2,4-dimethoxybenzyl)-N-(4-methoxyphenyl)amino)-3-oxopropanoate 

Relevant academic research and scientific papers

Regioselective access to substituted oxindoles via rhodium-catalyzed carbene C-H insertion

Rhodium-catalyzed decomposition of diazoamides followed by insertion of the resulting carbenes into an aromatic C-H bond gives access to substituted oxindoles. The reaction takes place with aromatic rings substituted by either electron-donating or -withdrawing groups at ortho, meta or para positions and the regioselectivity can be controlled by a substitution α to the diazo functionality. In the presence of an ester, the reaction leads to the formation of 2-silyloxyindole-3-carboxylates in 40-85% yields and regioselectivities up to 80% are observed in the case of meta-substituted substrates. This selectivity mainly relies on steric factors and use of a more bulky N,N-diethylamide then affords 2-silyloxyindole-3-carboxamides in 42-91% yields with complete regioselectivity.

Palladium asymmetric allylic alkylation of prochiral nucleophiles: Horsfiline

The asymmetric synthesis of the oxindole alkaloid horsfiline is described. A palladium-catalyzed asymmetric allylic alkylation (AAA) is used to set the spiro(pyrrolidine-oxindole) stereogenic center.