123794-61-6

Upstream product

• 103-82-2 phenylacetic acid 
• 599-67-7 1,1-diphenylethanol 
• 528-75-6 2,4-dinitrobenzaldehyde 
• 60-12-8 2-phenylethanol 
• 104-94-9 4-methoxy-aniline 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 629-11-8 1,6-hexanediol 
• 142-62-1 hexanoic acid 
• 111-27-3 hexan-1-ol 
• 590-92-1 3-Bromopropionic acid 
• 65-85-0 benzoic acid 

Downstream Products

• 891186-73-5 ethyl 2-diazo-3-(N-(2,4-dimethoxybenzyl)-N-(4-methoxyphenyl)amino)-3-oxopropanoate 
• 891186-81-5 (S)-1-(2,4-dimethoxybenzyl)-5-methoxy-1'-methylspiro[indoline-3,3'-pyrrolidine]-2,2'-dione 
• 891186-79-1 1-(2,4-dimethoxy-benzyl)-5-methoxy-2-oxo-3-(2-oxo-ethyl)-2,3-dihydro-1H-indole-3-carboxylic acid ethyl ester 
• 891186-77-9 3-allyl-1-(2,4-dimethoxy-benzyl)-5-methoxy-2-oxo-2,3-dihydro-1-H-indole-3-carboxylic acid ethyl ester 
• 891186-75-7 1-(2,4-dimethoxybenzyl)-5-methoxy-2-[(triisopropylsilyl)oxy]-1H-indole-3-carboxylic acid ethyl ester 
• 3446-77-3 (2,4-dimethoxy-benzyl)-(4-methoxy-phenyl)-amine 

Relevant academic research and scientific papers

Dialkyl diazomalonates in transition-metal-free, thermally promoted, diastereoselective wolff β-lactam synthesis

Metal-free, thermally promoted synthesis of 3-alkoxy-3-alkoxycarbonyl-2-azetidinones via the Wolff-Staudinger β-lactam synthesis using dialkyl diazomalonates is described. The reaction appears fairly general and delivers only one diastereomer.

Four acid-catalysed dehydration reactions proceed without interference

Four acid-catalysed dehydration reactions can proceed in one pot, simultaneously and without interference, to yield one imine, one acetal (or boronic ester), one ester and one alkene, even though many other cross-products could be conceived. This advanced

Palladium asymmetric allylic alkylation of prochiral nucleophiles: Horsfiline

The asymmetric synthesis of the oxindole alkaloid horsfiline is described. A palladium-catalyzed asymmetric allylic alkylation (AAA) is used to set the spiro(pyrrolidine-oxindole) stereogenic center.

2-Azetidinone cholesterol absorption inhibitors: Increased potency by substitution of the C-4 phenyl ring

SAR studies directed towards the optimization of 2-azetidinone cholesterol absorption inhibitors led to the discovery of 11a, the most potent cholesterol absorption inhibitor yet identified. Copyright (C) 1998 Elsevier Science Ltd.