344609-41-2

Basic information

• Product Name: Boc-[N-MeβAla]-o-Bzl
• Synonyms: Boc-[N-MeβAla]-o-Bzl
• CAS NO: 344609-41-2
• Molecular Weight: 293.363
• Mol File: 344609-41-2.mol

Chemical Properties

• CAS DataBase Reference: Boc-[N-MeβAla]-o-Bzl(CAS DataBase Reference)
• NIST Chemistry Reference: Boc-[N-MeβAla]-o-Bzl(344609-41-2)
• EPA Substance Registry System: Boc-[N-MeβAla]-o-Bzl(344609-41-2)

Safety Data

• Hazardous Substances Data: 344609-41-2(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 15761-38-3 L-N-Boc-Ala 
• 16948-16-6 N-(tert-butoxycarbonyl)-N-methyl-L-alanine 
• 100-39-0 benzyl bromide 

Downstream Products

• 133499-60-2 N^α-methylalanine benzyl ester 

Relevant articles and documents

Peptide Derivative

A pharmaceutical composition comprising a peptide derivative or its pharmaceutical equivalent salt having a general formula, R1N═C(R2)-AA1-AA2-AA3-AA4-Y, in which R1 is such as a

Solid-phase synthesis and configurational reassigment of callipeltin E. Implications for the structures of callipeltins A and B

Two possible isomers of the natural product callipeltin E (1, 5) were synthesized by using an Fmoc-based solid-phase strategy in 7 steps, in 20% and 26% overall yields, respectively. The 1H NMR spectrum of synthetic 5 correlated closely with that of the natural product, whereas that of 1 did not, providing confirmation of the configurational reassignment of the N-terminal residue of callipeltin E as D-allothreonine. This result strongly implies that the corresponding residue in the closely related cyclic depsipeptides callipeltins A and B should also be considered a D-allothreonine residue.

A racemization-free coupling method for peptides having N-methylamino acids at the carboxy-termini

To search for racemization-free coupling conditions for peptides having N-alkylamino acids at the carboxy-termini, a model coupling using Boc-Phe- MeAla-OH (MeAla, N-methylalanine) and H-Phe-OBzl was studied. When benzotriazolyl-N-oxytris(dimethylamino)ph

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