3447-09-4

Basic information

• Product Name: 1-Methyl-2-tetradecylpyrrolidine
• Synonyms: 1-Methyl-2-tetradecylpyrrolidine
• CAS NO: 3447-09-4
• Molecular Formula: C₁₉H₃₉N
• Molecular Weight: 0
• Mol File: 3447-09-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Methyl-2-tetradecylpyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2-tetradecylpyrrolidine(3447-09-4)
• EPA Substance Registry System: 1-Methyl-2-tetradecylpyrrolidine(3447-09-4)

Safety Data

• Hazardous Substances Data: 3447-09-4(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 1008797-49-6 2-tetradecylpyrrolidine 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 88303-25-7 tetradecylmagnesium bromide 

Relevant articles and documents

Chemoselective reductive alkynylation of tertiary amides by Ir and Cu(i) bis-metal sequential catalysis

We report herein a convenient and versatile method for the direct reductive alkynylation of tertiary amides to give propargylic amines through sequential Ir-catalysed hydrosilylation-Cu(i)-catalysed alkynylation. The reactions proceed chemoselectively at the amide group in the presence of several sensitive functional groups including the very reactive aldehyde group on either the amide or the alkyne coupling partner. The method is general for tert-amides with or without α-hydrogen.

Versatile one-pot reductive alkylation of lactams/amides via amide activation: Application to the concise syntheses of bioactive alkaloids (±)-bgugaine, (±)-coniine, (+)-preussin, and (-)-cassine

Direct entry: One-pot reductive alkylation of lactams/amides with Grignard reagents has been realized via lactam/amide activation with Tf2O. This method opens a direct entry to α-alkylated amines. The versatility of the method is illustrated by the concise syntheses of bioactive alkaloids (±)-bgugaine, (±)-coniine, (+)-preussin, and (?)-cassine.