344750-15-8

Basic information

• Product Name: (3-AMINO-PHENYL)-METHANESULFONAMIDE
• Synonyms: (3-AMINO-PHENYL)-METHANESULFONAMIDE;3-AMino-benzeneMethanesulfonaMide;1-(3-aminophenyl)methanesulfonamide
• CAS NO: 344750-15-8
• Molecular Formula: C₇H₁₀N₂O₂S
• Molecular Weight: 186.23
• Mol File: 344750-15-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-AMINO-PHENYL)-METHANESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-AMINO-PHENYL)-METHANESULFONAMIDE(344750-15-8)
• EPA Substance Registry System: (3-AMINO-PHENYL)-METHANESULFONAMIDE(344750-15-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 344750-15-8(Hazardous Substances Data)

Usage

Uses

3-Amino-benzenemethanesulfonamide can be used to synthesize disubstituted pyridine derivatives as inhibitors of the protein cyclin-dependent kinase (CDK).

Upstream product

• 58032-84-1 (3-nitrophenyl)methanesulfonyl chloride 
• 110654-66-5 (3-nitrophenyl)methanesulfonamide 

Downstream Products

• 1073484-21-5 (3-[6-(2-ethoxy-phenyl)-pyrimidin-4-ylamino]-phenyl)-methanesulfonamide 
• 1073484-51-1 (3-[6-(2-ethyl-phenyl)-pyrimidin-4-ylamino]-phenyl)-methanesulfonamide 
• 1073484-96-4 (3-[2-amino-6-(2-methoxy-phenyl)-pyrimidin-4-ylamino]-phenyl)-methanesulfonamide 
• 1073485-15-0 (3-(6-[2-(2-methoxy-ethoxy)-phenyl]-pyrimidin-4-ylamino)-phenyl)-methanesulfonamide 
• 1073485-16-1 (3-(6-[2-(tetrahydro-furan-2-ylmethoxy)-phenyl]-pyrimidin-4-ylamino)-phenyl)-methanesulfonamide 
• 1073485-17-2 (3-(6-[2-(2-methoxy-ethoxy)-phenyl]-2-methyl-pyrimidin-4-ylamino)-phenyl)-methanesulfonamide 
• 1335490-10-2 3-[(4-chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide 
• 1335491-38-7 3-[(4-(2-methoxyphenyl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide trifluoroacetate 
• 1335490-37-3 1-(3-{[4-(2-methoxyphenyl)-1,3,5-triazin-2-yl]amino}phenyl)methanesulfonamide 
• 1395493-47-6 [3-((4-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)amino)phenyl]methanesulfonamide 
• 1396707-40-6 3-[(4-(piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethane sulfonamide 
• 1073485-20-7 1073485-20-7P 
• 1335491-15-0 1-[3-({4-[4-fluoro-2-(trifluoromethyl)phenyl]-1,3,5-triazin-2-yl}-amino)phenyl]methanesulfonamide 
• 1335491-22-9 N-[5-fluoro-2-(4-{[3-(sulfamoylmethyl)phenyl]amino}-1,3,5-triazin-2-yl)phenyl]acetamide 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ABNORMAL CELLULAR PROLIFERATION

This invention is in the area of heterocyclic-based compounds for the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers.

INHIBITORS OF PROTEIN KINASES

The present invention relates to inhibitors of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to methods of preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases comprising the administration of an effective amount of at least one inhibitor of cyclin-dependent kinases.

4, 6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES

The present invention relates to inhibitors of general Formula (I) of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to compounds for preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases.