344751-54-8Relevant academic research and scientific papers
RE-EXPLORATION OF THE THERMOLYSIS OF ARYLAZIDES AS A ROUTE TO 3H-AZEPINES: CHEMISTRY OF AZIDOACETOPHENONES
Ohba, Yoshihiro,Kubo, Shinji,Nishiwaki, Tarozaemon,Aratani, Noritoshi
, p. 457 - 460 (2007/10/02)
Thermolysis of 3-azidoacetophenone in methanol in a sealed glass ampoule gave 6-acetyl- and 4-acetyl-3H-azepines in moderate yields, whose kinetic data a=132.6+/-1.7 kJmol-1, ΔS443= -12.1=/-4.2 JK-1mol-1> were obtained by means of HPLC.Photolysis of this azide in methanol gave the same pair of the 3H-azepines in poor yields.Thermolysis of 4-azidoacetphenone under the similar conditions afforded a moderate yield of 5-acetyl-3H-azepine.For comparison, photolyses of 4- and 2-azidoacetophenones were also studied.
