344779-31-3 Usage
Chemical Class
Benzisoxazoles Heterocyclic compounds containing a benzene ring fused to an isoxazole ring.
Structural Feature
5-chloro substitution A chloro group is added to the fifth position of the benzisoxazol-3(1H)-one core, potentially altering its chemical and pharmacological properties.
Potential Applications
Pharmaceutical and medicinal chemistry The compound can be used as a chemical building block or as a starting material for the synthesis of new drug candidates with tailored biological activities.
Property Investigation
Biological, toxicological, and physical properties Further research and characterization are needed to understand the specific properties of 2,1-Benzisoxazol-3(1H)-one, 5-chloro-(9CI) and its potential effects on living organisms and pharmacological applications.
Check Digit Verification of cas no
The CAS Registry Mumber 344779-31-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,4,7,7 and 9 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 344779-31:
(8*3)+(7*4)+(6*4)+(5*7)+(4*7)+(3*9)+(2*3)+(1*1)=173
173 % 10 = 3
So 344779-31-3 is a valid CAS Registry Number.
344779-31-3Relevant articles and documents
Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials
Snyder, Lawrence B.,Meng, Zhaoxing,Mate, Robert,D'Andrea, Stanley V.,Marinier, Anne,Quesnelle, Claude A.,Gill, Patrice,Den Bleyker, Kenneth L.,Fung-Tomc, Joan C.,Frosco, MaryBeth,Martel, Alain,Barrett, John F.,Bronson, Joanne J.
, p. 4735 - 4739 (2007/10/03)
A series of potential antimicrobial derivatives possessing bioisosteric replacements for the central oxazolidinone ring found in oxazolidinone antibacterials have been prepared. The design concept involved replacement of the requisite sp3-hybridized stereogenic center found at the 5-position of the oxazolidinone with a nitrogen atom. The synthesis and antibacterial activity of three such ring systems, the benzisoxazolinones, pyrroles, and isoxazolinones is described.
