344779-64-2

Upstream product

• 108-24-7 acetic anhydride 
• 23600-10-4 [(1R,2S,3R,4R,5S)-5-Benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2,3-dihydroxy-cyclohexyl]-carbamic acid benzyl ester 

Downstream Products

• 344779-65-3 Acetic acid (1S,2S,3R,4S,6R)-2-allyloxy-4,6-bis-benzyloxycarbonylamino-3-((2S,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-benzyloxycarbonylamino-tetrahydro-pyran-2-yloxy)-cyclohexyl ester 
• 344779-68-6 [(1R,2S,3R,4R,5S)-3-(2-Amino-ethoxy)-5-benzyloxycarbonylamino-4-((2S,3R,4R,5S,6R)-3-benzyloxycarbonylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyl]-carbamic acid benzyl ester 
• 344779-66-4 Acetic acid (1S,2S,3R,4S,6R)-4,6-bis-benzyloxycarbonylamino-3-((2S,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-benzyloxycarbonylamino-tetrahydro-pyran-2-yloxy)-2-(2-oxo-ethoxy)-cyclohexyl ester 
• 344779-67-5 Acetic acid (1S,2S,3R,4S,6R)-2-(2-azido-ethoxy)-4,6-bis-benzyloxycarbonylamino-3-((2S,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-benzyloxycarbonylamino-tetrahydro-pyran-2-yloxy)-cyclohexyl ester 
• 344779-70-0 Acetic acid (1S,2S,3R,4S,6R)-4,6-bis-benzyloxycarbonylamino-2-[2-(2-benzyloxycarbonylamino-ethylamino)-ethoxy]-3-((2S,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-benzyloxycarbonylamino-tetrahydro-pyran-2-yloxy)-cyclohexyl ester 
• 344779-94-8 4-{2-[(1S,2S,3R,5S,6R)-2-Acetoxy-3,5-bis-benzyloxycarbonylamino-6-((2S,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-benzyloxycarbonylamino-tetrahydro-pyran-2-yloxy)-cyclohexyloxy]-ethyl}-piperazine-1-carboxylic acid benzyl ester 
• 344779-92-6 Acetic acid (1S,2S,3R,4S,6R)-4,6-bis-benzyloxycarbonylamino-2-[2-(5-benzyloxycarbonylamino-pentylamino)-ethoxy]-3-((2S,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-benzyloxycarbonylamino-tetrahydro-pyran-2-yloxy)-cyclohexyl ester 
• 344779-93-7 C₅₉H₇₉N₇O₂₁ 
• 344779-95-9 Acetic acid (1S,2S,3R,4S,6R)-4,6-bis-benzyloxycarbonylamino-2-{2-[bis-(2-benzyloxycarbonylamino-ethyl)-amino]-ethoxy}-3-((2S,3R,4R,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-3-benzyloxycarbonylamino-tetrahydro-pyran-2-yloxy)-cyclohexyl ester 

Relevant academic research and scientific papers

Design, modeling and synthesis of functionalized paromamine analogs

Based on the published NMR structure of the antibiotic paromomycin complexed with the A-site of Escherichia coli 16S ribosomal RNA, a set of C-5 functionalized analogs of paromamine was designed and synthesized, incorporating cyclic and acyclic appendages and terminating with one or more ammonium groups.