344906-03-2Relevant articles and documents
Conformation-specific cleavage of antisense oligonucleotide-RNA duplexes by RNase H
Pradeepkumar, Pushpangadan I.,Zamaratski, Edouard,Foeldesi, Andras,Chattopadhyaya, Jyoti
, p. 402 - 408 (2007/10/03)
The North-form (3'-endo) constrained 1-(1',3'-O-anhydro-β-D-psicofuranosyl)thymine block, , was systematically incorporated at various sites, one at a time, into a set of four antisense oligonucleotides (AONs). The hybrids of these AONs with a matched