344905-99-3Relevant articles and documents
Synthesis of anhydro psicofuranosyl nucleosides
Roivainen, Jarkko,Veps?l?inen, Jouko,Azhayev, Alex,Mikhailopulo, Igor A.
, p. 6553 - 6555 (2002)
Methyl 1-O-mesyl-5-O-toluoyl-β-D-psicofuranoside (5) was synthesised from the known 1,3;4,5-di-O-isopropylidene-β-D-psicofuranose (1) as a key carbohydrate precursor for the preparation of anhydro psicofuranosyl nucleosides. Transformation of 5 into aceta
ODCASE INHIBITORS FOR THE TREATMENT OF MALARIA
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Page/Page column 46; 48, (2008/06/13)
The present invention includes methods of treating or preventing malaria by administering an anti-malarial effective amount of 6-substituted uridine derivatives to a subject need thereof. The invention also includes new 6-substituted uridine derivatives for use as therapeutics, in particular to treat malaria.
Conformation-specific cleavage of antisense oligonucleotide-RNA duplexes by RNase H
Pradeepkumar, Pushpangadan I.,Zamaratski, Edouard,Foeldesi, Andras,Chattopadhyaya, Jyoti
, p. 402 - 408 (2007/10/03)
The North-form (3'-endo) constrained 1-(1',3'-O-anhydro-β-D-psicofuranosyl)thymine block, , was systematically incorporated at various sites, one at a time, into a set of four antisense oligonucleotides (AONs). The hybrids of these AONs with a matched