345-72-2 Usage
General Description
ETHYL 3-FLUORO-4-METHOXYBENZOYLFORMATE is a chemical compound with the molecular formula C11H11FO4. It is also known as ethyl 3-fluoro-4-methoxybenzoylformate. ETHYL 3-FLUORO-4-METHOXYBENZOYLFORMATE is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. It is often employed in organic synthesis as a reagent for the preparation of various functionalized aromatic compounds. ETHYL 3-FLUORO-4-METHOXYBENZOYLFORMATE is a colorless liquid with a sweet odor and is considered to be a potentially hazardous substance that should be handled with care and in accordance with safety guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 345-72-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,4 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 345-72:
(5*3)+(4*4)+(3*5)+(2*7)+(1*2)=62
62 % 10 = 2
So 345-72-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H11FO4/c1-3-16-11(14)10(13)7-4-5-9(15-2)8(12)6-7/h4-6H,3H2,1-2H3
345-72-2Relevant articles and documents
Selective Acylation of Aryl- A nd Heteroarylmagnesium Reagents with Esters in Continuous Flow
Heinz, Benjamin,Djukanovic, Dimitrije,Ganiek, Maximilian A.,Martin, Benjamin,Schenkel, Berthold,Knochel, Paul
supporting information, p. 493 - 496 (2020/01/31)
A selective acylation of readily accessible organomagnesium reagents with commercially available esters proceeds at convenient temperatures and short residence times in continuous flow. Flow conditions allow us to prevent premature collapse of the hemiacetal intermediates despite noncryogenic conditions, thus furnishing ketones in good yields. Throughout, the coordinating ability of the ester and/or Grignard was crucial for the reaction outcome. This was leveraged by the obtention of several bisaryl ketones using 2-hydroxy ester derivatives as substrates.
