345-72-2 Usage
Uses
Used in Pharmaceutical Industry:
ETHYL 3-FLUORO-4-METHOXYBENZOYLFORMATE is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique chemical structure allows for the creation of a variety of functionalized aromatic compounds, which are essential in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, ETHYL 3-FLUORO-4-METHOXYBENZOYLFORMATE serves as a key component in the synthesis of various agrochemicals, including pesticides and herbicides. Its role in developing effective and targeted agrochemicals is vital for agricultural productivity and crop protection.
Used in Organic Synthesis:
ETHYL 3-FLUORO-4-METHOXYBENZOYLFORMATE is utilized as a reagent in organic synthesis for the preparation of a range of functionalized aromatic compounds. Its versatility in forming different chemical entities makes it a valuable asset in the synthesis of complex organic molecules for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 345-72-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,4 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 345-72:
(5*3)+(4*4)+(3*5)+(2*7)+(1*2)=62
62 % 10 = 2
So 345-72-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H11FO4/c1-3-16-11(14)10(13)7-4-5-9(15-2)8(12)6-7/h4-6H,3H2,1-2H3
345-72-2Relevant academic research and scientific papers
Selective Acylation of Aryl- A nd Heteroarylmagnesium Reagents with Esters in Continuous Flow
Heinz, Benjamin,Djukanovic, Dimitrije,Ganiek, Maximilian A.,Martin, Benjamin,Schenkel, Berthold,Knochel, Paul
supporting information, p. 493 - 496 (2020/01/31)
A selective acylation of readily accessible organomagnesium reagents with commercially available esters proceeds at convenient temperatures and short residence times in continuous flow. Flow conditions allow us to prevent premature collapse of the hemiacetal intermediates despite noncryogenic conditions, thus furnishing ketones in good yields. Throughout, the coordinating ability of the ester and/or Grignard was crucial for the reaction outcome. This was leveraged by the obtention of several bisaryl ketones using 2-hydroxy ester derivatives as substrates.
&α,&α-Difluoroarylacetic Acids: Preparation from (Diethylamino)sulfur Trifluoride and &α-Oxoarylacetates
Middleton, W. J.,Bingham, E. M.
, p. 2883 - 2887 (2007/10/02)
Several α,α-difluoroarylacetic acids have been prepared by reaction of DAST ((diethylamino)sulfur trifluoride) with esters of α-oxoarylacetic acids and then hydrolysis of the resulting difluoro ester.Examples include the α,α-difluoro derivates of the synthetic plant auxin, α-naphthylacetic acid, and the antiinflammatory drug, ibufenac.
