34522-48-0Relevant articles and documents
Efficient and Clean Nickel Catalyzed α-Allylation Reaction of Nitriles
Mouhsine, Bouchaib,Karim, Abdallah,Dumont, Clément,Suisse, Isabelle,Sauthier, Mathieu
supporting information, p. 1457 - 1462 (2021/02/16)
A clean method has been developed for the α-allylation of phenyl and alpha alkyl phenyl acetonitrile with allylic alcohols. The reaction is catalyzed by nickel complexes in situ generated from a combination of Ni(cod)2 and the dppf ligand and performed at 80 °C in methanol as reaction solvent.Accordingly to this simple and base-free protocol that only yields water as a side-product, many allylic nitriles were synthetized with good yields. (Figure presented.).
Room temperature hydroamination of N-alkenyl ureas catalyzed by a gold(I) N-heterocyclic carbene complex
Bender, Christopher F.,Widenhoefer, Ross A.
, p. 5303 - 5305 (2007/10/03)
Treatment of an N-4-pentenyl or N-5-hexenyl urea with a catalytic 1:1 mixture of a gold(I) N,N-diaryl imidazol-2-ylidine complex and AgOTf at or near room temperature leads to intramolecular exo-hydroamination to form the corresponding nitrogen heterocycle in excellent yield.
