345221-63-8Relevant academic research and scientific papers
Palladium-catalyzed synthesis of cephalotaxine analogues
Tietze, Lutz F.,Schirok, Hartmut,Woehrmann, Michael
, p. 510 - 518 (2007/10/03)
The synthesis of cephalotaxine ring analogues 10 was achieved by two successive intramolecular palladium-catalyzed reactions of 12 via 11, namely an allylic amination and a Heck reaction. The substrates 12 were obtained by alkylation of primary amines 13 with tosylates 14.
Enantioselective highly efficient synthesis of (-)-cephalotaxine using two palladium-catalyzed transformations
Tietze, Lutz F.,Schirok, Hartmut
, p. 10264 - 10269 (2007/10/03)
Cephalotaxine (1), the major alkaloid isolated from Cephalotaxus species, has attracted considerable attention due to the promising antitumor activity of several of its derivatives and its unique structural features. Herein we describe a highly efficient
PALLADIUM ASSISTED SYNTHESIS OF 1-AZASPIROCYCLES
Godleski, Stephen A.,Meinhart, James D.,Miller, David J.,Wallendael, Shawn Van
, p. 2247 - 2250 (2007/10/02)
A facile, general route to 1-azaspirocycles utilizing a ?-allyl palladium complex in the key cyclization step has been developed.
