345227-52-3Relevant academic research and scientific papers
PYRROLOINDOLES. 6. NEW SYNTHESIS OF 1H,5H-PYRROLOINDOLE AND 3H,6H-PYRROLOINDOLE
Samsoniya, Sh. A.,Kadzhrishvili, D. O.,Gordeev, E. N.,Zhigachev, V. E.,Kurkovskaya, L. N.,Suvorov, N. N.
, p. 382 - 385 (2007/10/02)
Ethyl pyruvate 1-acetyl-5-indolinylhydrazone was obtained by diazotization of 1-acetyl-5-aminoindoline with subsequent reduction of the diazonium salt and condensation of the hydrazine with ethyl pyruvate.A mixture of hydrogenated derivatives of linear and angular pyrroloindoles is formed as a result of cyclization of the hydrazone in polyphosphoric acid esters.Subsequent hydrolysis, decarboxylation, and dehydrogenation lead to 1H,5H-pyrroloindole and 3H,6H-pyrroloindole.
