345233-97-8

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 87572-56-3 (E)-5-(2-bromovinyl)-3'-O-(N-Boc-L-phenylalaninyl)-2'-deoxyuridine 
• 376393-38-3 5'-O-tert-butyldimethylsilyl-(E)-5-(2-bromovinyl)-2'-deoxyuridine 
• 192752-93-5 3-methylsalicylchlorophosphane 
• 69304-47-8 (E)-5-(2-bromovinyl)-2'-deoxyuridine 

Downstream Products

• 80860-82-8 (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-monophosphate 

Relevant academic research and scientific papers

Synthesis, hydrolysis and anti-EBV activity of a series of 3′-modified cycloSal-BVDUMP pronucleotides

A series of cycloSal-BVDUMP phosphate triesters has been prepared. The prototype compound was 3-methyl-cycloSal-BVDUMP 2. Furthermore, a series of 3′-O-acyl-modified derivatives having carboxylic acids with different lipophilicity or a L-configurated α-am

CycloSal-BVDUMP pronucleotides: How to convert an antiviral-inactive nucleoside analogue into a bioactive compound against EBV

Novel cycloSal-BVDUMP triesters 2-4 5-[(E)-2-bromovinyl]-2′-deoxyuridine (BVDU, 1) have been studied with regard to their potential anti-EBV activity. In addition to the 3′-unmodified cycloSal-BVDUMP triesters 2a-f, the 3′-hydroxyl function has been ester