87572-56-3Relevant academic research and scientific papers
CycloSal-BVDUMP pronucleotides: How to convert an antiviral-inactive nucleoside analogue into a bioactive compound against EBV
Meier, Chris,Lomp, Andreas,Meerbach, Astrid,Wutzler, Peter
, p. 5157 - 5172 (2007/10/03)
Novel cycloSal-BVDUMP triesters 2-4 5-[(E)-2-bromovinyl]-2′-deoxyuridine (BVDU, 1) have been studied with regard to their potential anti-EBV activity. In addition to the 3′-unmodified cycloSal-BVDUMP triesters 2a-f, the 3′-hydroxyl function has been ester
Synthesis, hydrolysis and anti-EBV activity of a series of 3′-modified cycloSal-BVDUMP pronucleotides
Meier,Lomp,Meerbach,Wutzler
, p. 307 - 314 (2007/10/03)
A series of cycloSal-BVDUMP phosphate triesters has been prepared. The prototype compound was 3-methyl-cycloSal-BVDUMP 2. Furthermore, a series of 3′-O-acyl-modified derivatives having carboxylic acids with different lipophilicity or a L-configurated α-am
